2V8X

Crystallographic and mass spectrometric characterisation of eIF4E with N7-cap derivatives

Summary for 2V8X

Entry DOI	10.2210/pdb2v8x/pdb
Related	1IPB 1IPC 2JGB 2JGC 2V8W 2V8Y
Descriptor	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1, 7-BENZYL GUANINE MONOPHOSPHATE, ... (4 entities in total)
Functional Keywords	translation, phosphorylation, initiation factor, cap, eif4e, 7bngmp, 4e-bp1, rna-binding, acetylation, host-virus interaction, protein synthesis inhibitor, protein biosynthesis, translation regulation
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	4
Total formula weight	54891.67
Authors	Brown, C.J.,Mcnae, I.,Fischer, P.M.,Walkinshaw, M.D. (deposition date: 2007-08-16, release date: 2007-08-28, Last modification date: 2023-12-13)
Primary citation	Brown, C.J.,Mcnae, I.,Fischer, P.M.,Walkinshaw, M.D. Crystallographic and Mass Spectrometric Characterisation of Eif4E with N(7)-Alkylated CAP Derivatives. J.Mol.Biol., 372:7-, 2007 Cited by PubMed: 17631896 DOI: 10.1016/J.JMB.2007.06.033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation