2J0T
Crystal Structure of the Catalytic Domain of MMP-1 in Complex with the Inhibitory Domain of TIMP-1
Summary for 2J0T
Entry DOI | 10.2210/pdb2j0t/pdb |
Related | 1AYK 1CGE 1CGF 1CGL 1D2B 1HFC 1LQN 1OO9 1SU3 1UEA 2AYK 2CLT 2TCL 3AYK 4AYK 966C |
Descriptor | INTERSTITIAL COLLAGENASE, METALLOPROTEINASE INHIBITOR 1, ZINC ION, ... (5 entities in total) |
Functional Keywords | extracellular matrix, erythrocyte maturation, autocatalytic cleavage, collagen degradation, hydrolase |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P03956 Secreted: P01033 |
Total number of polymer chains | 6 |
Total formula weight | 100551.29 |
Authors | Iyer, S.,Wei, S.,Brew, K.,Acharya, K.R. (deposition date: 2006-08-04, release date: 2006-10-18, Last modification date: 2023-12-13) |
Primary citation | Iyer, S.,Wei, S.,Brew, K.,Acharya, K.R. Crystal Structure of the Catalytic Domain of Matrix Metalloproteinase-1 in Complex with the Inhibitory Domain of Tissue Inhibitor of Metalloproteinase-1. J.Biol.Chem., 282:364-, 2007 Cited by PubMed: 17050530DOI: 10.1074/JBC.M607625200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.54 Å) |
Structure validation
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