2TCL

STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST COLLAGENASE COMPLEXED WITH AN INHIBITOR

Summary for 2TCL

Entry DOI	10.2210/pdb2tcl/pdb
Descriptor	FIBROBLAST COLLAGENASE, ZINC ION, SAMARIUM (III) ION, ... (6 entities in total)
Functional Keywords	hydrolase (metalloprotease)
Biological source	Homo sapiens (human)
Cellular location	Secreted, extracellular space, extracellular matrix (Probable): P03956
Total number of polymer chains	1
Total formula weight	19628.37
Authors	Winkler, F.K.,Borkakoti, N.,D'Arcy, A. (deposition date: 1994-09-07, release date: 1996-03-08, Last modification date: 2024-02-21)
Primary citation	Borkakoti, N.,Winkler, F.K.,Williams, D.H.,D'Arcy, A.,Broadhurst, M.J.,Brown, P.A.,Johnson, W.H.,Murray, E.J. Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor. Nat.Struct.Biol., 1:106-110, 1994 Cited by PubMed: 7656013 DOI: 10.1038/nsb0294-106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation