2CLT
Crystal structure of the active form (full-length) of human fibroblast collagenase.
Summary for 2CLT
Entry DOI | 10.2210/pdb2clt/pdb |
Related | 1AYK 1CGE 1CGF 1CGL 1HFC 1SU3 2AYK 2TCL 3AYK 4AYK 966C |
Descriptor | INTERSTITIAL COLLAGENASE, CALCIUM ION, ZINC ION, ... (4 entities in total) |
Functional Keywords | extracellular matrix, fibroblast collagenase, zinc, calcium, zymogen, protease, collagen, autocatalytic cleavage, matrix metalloproteinases, hydrolase, polymorphism, glycoprotein, metal-binding, inhibitor-free, metalloprotease, collagen degradation |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P03956 |
Total number of polymer chains | 2 |
Total formula weight | 85042.40 |
Authors | Iyer, S.,Visse, R.,Nagase, H.,Acharya, K.R. (deposition date: 2006-04-29, release date: 2006-08-09, Last modification date: 2023-12-13) |
Primary citation | Iyer, S.,Visse, R.,Nagase, H.,Acharya, K.R. Crystal Structure of an Active Form of Human Mmp-1. J.Mol.Biol., 362:78-, 2006 Cited by PubMed: 16890240DOI: 10.1016/J.JMB.2006.06.079 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.67 Å) |
Structure validation
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