2CLT
Crystal structure of the active form (full-length) of human fibroblast collagenase.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | INTERSTITIAL COLLAGENASE | polymer | 367 | 42230.1 | 2 | UniProt (P03956) Pfam (PF00413) Pfam (PF00045) | HOMO SAPIENS (HUMAN) | MATRIX METALLOPROTEINASE - 1, MMP-1, FIBROBLAST COLLAGENASE |
| 2 | C, D, E, F, I... (A, B) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 3 | G, H, M, N (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | O, P (A, B) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A, B: 81 - 447 (UniProt: P03956)
| PDB | External Database | Details |
|---|---|---|
| Ala 200 | Glu 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84460.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 582.3 | |
| All* | Total formula weight | 85042.4 |
