2CLE

Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2- amino-1-ethylphosphate (F6) - lowF6 complex

Summary for 2CLE

• Entry DOI: 10.2210/pdb2cle/pdb
• Related: 1A50 1A5A 1A5B 1A5S 1BEU 1BKS 1C29 1C8V 1C9D 1CW2 1CX9 1FUY 1K3U 1K7E 1K7F 1K7X 1K8X 1K8Y 1K8Z 1KFB 1KFC 1KFE 1KFJ 1KFK 1QOP 1QOQ 1TJP 1TTP 1TTQ 1UBS 1WBJ 2CLF 2CLH 2CLI 2CLK 2CLL 2CLM 2CLO 2TRS 2TSY 2TYS 2WSY
• Descriptor: TRYPTOPHAN SYNTHASE ALPHA CHAIN, TRYPTOPHAN SYNTHASE BETA CHAIN, SODIUM ION, ... (6 entities in total)
• Functional Keywords: aromatic amino acid biosynthesis, tryptophan biosynthesis, crbon- oxygen lyase, amino-acid biosynthesis, lyase, allosteric enzyme, pyridoxal phosphate
• Biological source: SALMONELLA TYPHIMURIUM; More
• Total number of polymer chains: 2
• Total formula weight: 72155.90

Authors

Ngo, H.,Harris, R.,Kimmich, N.,Casino, P.,Niks, D.,Blumenstein, L.,Barends, T.R.,Kulik, V.,Weyand, M.,Schlichting, I.,Dunn, M.F. (deposition date: 2006-04-27, release date: 2007-06-12, Last modification date: 2011-07-13)

• Primary citation: Ngo, H.,Harris, R.,Kimmich, N.,Casino, P.,Niks, D.,Blumenstein, L.,Barends, T.R.,Kulik, V.,Weyand, M.,Schlichting, I.,Dunn, M.F.; Synthesis and Characterization of Allosteric Probes of Substrate Channeling in the Tryptophan Synthase Bienzyme Complex.; Biochemistry, 46:7713-, 2007; PubMed: 17559195; DOI: 10.1021/BI700385F

Experimental method

X-RAY DIFFRACTION (1.5 Å)