2TSY

CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES

Summary for 2TSY

Entry DOI	10.2210/pdb2tsy/pdb
Descriptor	TRYPTOPHAN SYNTHASE, SN-GLYCEROL-3-PHOSPHATE, SODIUM ION, ... (6 entities in total)
Functional Keywords	lyase, carbon-oxygen lyase, tryptophan biosynthesis, pyridoxal phosphate
Biological source	Salmonella typhimurium More
Total number of polymer chains	2
Total formula weight	72175.06
Authors	Rhee, S.,Parris, K.D.,Hyde, C.C.,Ahmed, S.A.,Miles, E.W.,Davies, D.R. (deposition date: 1997-01-03, release date: 1997-04-01, Last modification date: 2024-02-21)
Primary citation	Rhee, S.,Parris, K.D.,Hyde, C.C.,Ahmed, S.A.,Miles, E.W.,Davies, D.R. Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes. Biochemistry, 36:7664-7680, 1997 Cited by PubMed: 9201907 DOI: 10.1021/bi9700429 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation