2TRS
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
Summary for 2TRS
Entry DOI | 10.2210/pdb2trs/pdb |
Descriptor | TRYPTOPHAN SYNTHASE, INDOLE-3-PROPANOL PHOSPHATE, SODIUM ION, ... (6 entities in total) |
Functional Keywords | lyase, carbon-oxygen lyase, tryptophan biosynthesis, pyridoxal phosphate |
Biological source | Salmonella typhimurium More |
Total number of polymer chains | 2 |
Total formula weight | 72258.19 |
Authors | Rhee, S.,Parris, K.D.,Hyde, C.C.,Ahmed, S.A.,Miles, E.W.,Davies, D.R. (deposition date: 1997-01-07, release date: 1997-04-01, Last modification date: 2024-02-21) |
Primary citation | Rhee, S.,Parris, K.D.,Hyde, C.C.,Ahmed, S.A.,Miles, E.W.,Davies, D.R. Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes. Biochemistry, 36:7664-7680, 1997 Cited by PubMed: 9201907DOI: 10.1021/bi9700429 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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