2TRS
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TRYPTOPHAN SYNTHASE | polymer | 268 | 28698.8 | 1 | UniProt (P00929) Pfam (PF00290) In PDB | Salmonella typhimurium | |
| 2 | B | TRYPTOPHAN SYNTHASE | polymer | 397 | 42945.0 | 1 | UniProt (P0A2K1) Pfam (PF00291) In PDB | Salmonella typhimurium | |
| 3 | A | INDOLE-3-PROPANOL PHOSPHATE | non-polymer | 255.2 | 1 | Chemie (IPL) | |||
| 4 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | B | [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | non-polymer | 336.2 | 1 | Chemie (PLS) | |||
| 6 | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
B: 2 - 397 (UniProt: P0A2K1)
| PDB | External Database | Details |
|---|---|---|
| Thr 87 | Lys 86 | engineered mutation |
| Leu 396 | Glu 395 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71643.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 614.4 | |
| All* | Total formula weight | 72258.2 |
