1K8Y

CRYSTAL STRUCTURE OF THE TRYPTOPHAN SYNTHASE BETA-SER178PRO MUTANT COMPLEXED WITH D,L-ALPHA-GLYCEROL-3-PHOSPHATE

Summary for 1K8Y

Entry DOI	10.2210/pdb1k8y/pdb
Related	1K7X 1K8Z
Descriptor	TRYPTOPHAN SYNTHASE ALPHA CHAIN, TRYPTOPHAN SYNTHASE BETA CHAIN, 1,3-DIHYDROXYACETONEPHOSPHATE, ... (6 entities in total)
Functional Keywords	carbon-oxygen lyase, tryptophan biosynthesis, pyridoxal phosphate, lyase
Biological source	Salmonella typhimurium More
Total number of polymer chains	2
Total formula weight	71936.71
Authors	Weyand, M.,Schlichting, I.,Marabotti, A.,Mozzarelli, A. (deposition date: 2001-10-26, release date: 2002-06-19, Last modification date: 2023-08-16)
Primary citation	Weyand, M.,Schlichting, I.,Herde, P.,Marabotti, A.,Mozzarelli, A. Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme. J.Biol.Chem., 277:10653-10660, 2002 Cited by PubMed: 11756454 DOI: 10.1074/jbc.M111031200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation