2C9W
CRYSTAL STRUCTURE OF SOCS-2 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 1.9A RESOLUTION
Summary for 2C9W
Entry DOI | 10.2210/pdb2c9w/pdb |
Related | 1LM8 1LQB 1VCB |
Descriptor | SUPPRESSOR OF CYTOKINE SIGNALING 2, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... (6 entities in total) |
Functional Keywords | growth regulation, sh2 domain, signal transduction inhibitor, nuclear protein, transcription, transcription regulation, ubl conjugation pathway |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 3 |
Total formula weight | 43859.93 |
Authors | Debreczeni, J.E.,Bullock, A.,Amos, A.,Savitsky, P.,Barr, A.,Burgess, N.,Sundstrom, M.,Weigelt, J.,Arrowsmith, C.,Edwards, A.,Knapp, S. (deposition date: 2005-12-14, release date: 2006-02-22, Last modification date: 2023-12-13) |
Primary citation | Bullock, A.N.,Debreczeni, J.E.,Edwards, A.M.,Sundstrom, M.,Knapp, S. Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase. Proc. Natl. Acad. Sci. U.S.A., 103:7637-7642, 2006 Cited by PubMed: 16675548DOI: 10.1073/pnas.0601638103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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