1UXW

CRYSTAL STRUCTURE OF HLA-B*2709 COMPLEXED WITH THE LATENT MEMBRANE PROTEIN 2 PEPTIDE (LMP2) OF EPSTEIN-BARR VIRUS

1UXW の概要

• エントリーDOI: 10.2210/pdb1uxw/pdb
• 関連するPDBエントリー: 1A1M 1A1N 1A1O 1A6Z 1A9B 1A9E 1AGB 1AGC 1AGD 1AGE 1AGF 1AKJ 1AO7 1B0G 1B0R 1BD2 1C16 1CE6 1CG9 1DE4 1DUY 1DUZ 1E27 1E28 1EEY 1EEZ 1EFX 1EXU 1GZP 1GZQ 1HHG 1HHH 1HHI 1HHJ 1HHK 1HLA 1HSA 1HSB 1I1F 1I1Y 1I4F 1I7R 1I7T 1I7U 1IM3 1IM9 1JF1 1JGD 1JGE 1JHT 1JNJ 1K5N 1KPR 1KTL 1LDS 1LP9 1M05 1M6O 1MHE 1MI5 1OF2 1OGA 1OGT 1ONQ 1P7Q 1QEW 1QLF 1QQD 1QR1 1QRN 1QSE 1QSF 1TMC 1UQS 1UR7 1UXS 2CLR 2HLA 3HLA
• 分子名称: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN B-27 ALPHA CHAIN, BETA-2-MICROGLOBULIN, GENE TERMINAL PROTEIN (MEMBRANE PROTEIN LMP-2A/LMP-2B), ... (5 entities in total)
• 機能のキーワード: immune system-peptide complex, complex (antigen-peptide), immune system, mhc (major histocompatibility complex), hla- b*2709, immune system/peptide
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P03989; Secreted: P01884; Isoform LMP2A: Host cell membrane; Multi- pass membrane protein. Isoform LMP2B: Host endomembrane system; Multi-pass membrane protein: P13285
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45594.63

構造登録者

Hulsmeyer, M.,Kozerski, C.,Fiorillo, M.T.,Sorrentino, R.,Saenger, W.,Ziegler, A.,Uchanska-Ziegler, B. (登録日: 2004-03-01, 公開日: 2004-11-09, 最終更新日: 2023-12-13)

• 主引用文献: Fiorillo, M.T.,Ruckert, C.,Hulsmeyer, M.,Sorrentino, R.,Saenger, W.,Ziegler, A.,Uchanska-Ziegler, B.; Allele-Dependent Similarity between Viral and Self-Peptide Presentation by Hla-B27 Subtypes; J.Biol.Chem., 280:2962-, 2005; PubMed: 15537660; DOI: 10.1074/JBC.M410807200

実験手法

X-RAY DIFFRACTION (1.71 Å)