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1US0

Human Aldose Reductase in complex with NADP+ and the inhibitor IDD594 at 0.66 Angstrom

Summary for 1US0
Entry DOI10.2210/pdb1us0/pdb
Related1ABN 1ADS 1AZ1 1AZ2 1EF3 1EL3 1IEI 1MAR 2ACQ 2ACR 2ACS 2ACU
DescriptorALDOSE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, IDD594, ... (5 entities in total)
Functional Keywordsoxidoreductase, nadp, idd594
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total formula weight37444.25
Authors
Primary citationHoward, E.I.,Sanishvili, R.,Cachau, R.E.,Mitschler, A.,Chevrier, B.,Barth, P.,Lamour, V.,Van Zandt, M.,Sibley, E.,Bon, C.,Moras, D.,Schneider, T.R.,Joachimiak, A.,Podjarny, A.
Ultrahigh Resolution Drug Design I: Details of Interactions in Human Aldose Reductase-Inhibitor Complex at 0.66 A.
Proteins, 55:792-, 2004
Cited by
PubMed: 15146478
DOI: 10.1002/PROT.20015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (0.66 Å)
Structure validation

217705

건을2024-03-27부터공개중

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