1OEX

Atomic Resolution Structure of Endothiapepsin in Complex with a Hydroxyethylene Transition State Analogue Inhibitor H261

Summary for 1OEX

Entry DOI	10.2210/pdb1oex/pdb
Related	1E5O 1E80 1E81 1E82 1EED 1ENT 1EPL 1EPM 1EPN 1EPO 1EPP 1EPQ 1EPR 1ER8 1GKT 1GVT 1GVU 1GVV 1GVW 1GVX 1OD1 1OEW 2ER0 2ER6 2ER7 2ER9 3ER3 3ER5 4APE 4ER1 4ER2 4ER4 5ER1 5ER2
Related PRD ID	PRD_000266
Descriptor	ENDOTHIAPEPSIN, INHIBITOR H261, GLYCEROL, ... (5 entities in total)
Functional Keywords	aspartic proteinase mechanism, atomic resolution, succinimide, anisotropic refinement, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	CRYPHONECTRIA PARASITICA (CHESTNUT BLIGHT FUNGUS) More
Total number of polymer chains	2
Total formula weight	35308.45
Authors	Coates, L.,Erskine, P.T.,Mall, S.,Gill, R.S.,Wood, S.P.,Myles, D.A.A.,Cooper, J.B. (deposition date: 2003-03-31, release date: 2003-04-02, Last modification date: 2023-11-15)
Primary citation	Erskine, P.T.,Coates, L.,Mall, S.,Gill, R.S.,Wood, S.P.,Myles, D.A.A.,Cooper, J.B. Atomic Resolution Analysis of the Catalytic Site of an Aspartic Proteinase and an Unexpected Mode of Binding by Short Peptides Protein Sci., 12:1741-, 2003 Cited by PubMed: 12876323 DOI: 10.1110/PS.0305203 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation