Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 410 |
| Chain | Residue |
| A | CYS254 |
| A | ASP278 |
| A | GLY280 |
| A | PRO281 |
| A | CYS289 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 500 |
| Chain | Residue |
| A | HOH2473 |
| A | HOH2474 |
| A | HOH2475 |
| A | TYR178 |
| A | SER181 |
| A | ILE182 |
| A | HOH2329 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | SER112 |
| A | SER113 |
| A | THR321 |
| A | HOH2180 |
| A | HOH2221 |
| A | HOH2476 |
| A | HOH2477 |
| A | HOH2478 |
| A | HOH2479 |
| A | HOH2480 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | SER136 |
| A | PRO137 |
| A | HOH2481 |
| A | HOH2483 |
| A | HOH2484 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| Chain | Residue |
| A | ALA268 |
| A | ARG269 |
| A | SER283 |
| A | HOH2331 |
| A | HOH2416 |
| A | HOH2437 |
| A | HOH2467 |
| A | HOH2485 |
| site_id | AC6 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR CHAIN B OF INHIBITOR H261 |
| Chain | Residue |
| A | LEU13 |
| A | ASP15 |
| A | ASP33 |
| A | ASP35 |
| A | GLY37 |
| A | SER77 |
| A | TYR78 |
| A | GLY79 |
| A | ASP80 |
| A | SER82 |
| A | ASP118 |
| A | ILE121 |
| A | LEU132 |
| A | PHE193 |
| A | ASP218 |
| A | GLY220 |
| A | THR221 |
| A | THR222 |
| A | PHE279 |
| A | GLY280 |
| A | PRO281 |
| A | ILE282 |
| A | HOH2170 |
| B | HOH2002 |
| B | HOH2003 |
| B | HOH2004 |
| B | HOH2005 |
| B | HOH2006 |
| B | HOH2008 |
| B | HOH2009 |
| B | HOH2010 |
| B | HOH2011 |
| B | HOH2012 |
| B | HOH2013 |
| B | HOH2014 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | ILE216-PRO227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP35 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP218 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR221 | |
| A | SER38 | |
| A | ASP35 | |
| A | ASP218 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP35 | |
| A | ASP218 | |
| A | THR219 | |
| A | THR36 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER38 | |
| A | ASP35 | |
| A | ASP218 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR221 | |
| A | ASP35 | |
| A | ASP218 | |
| A | THR36 | |
