1OEX

Atomic Resolution Structure of Endothiapepsin in Complex with a Hydroxyethylene Transition State Analogue Inhibitor H261

1OEX の概要

• エントリーDOI: 10.2210/pdb1oex/pdb
• 関連するPDBエントリー: 1E5O 1E80 1E81 1E82 1EED 1ENT 1EPL 1EPM 1EPN 1EPO 1EPP 1EPQ 1EPR 1ER8 1GKT 1GVT 1GVU 1GVV 1GVW 1GVX 1OD1 1OEW 2ER0 2ER6 2ER7 2ER9 3ER3 3ER5 4APE 4ER1 4ER2 4ER4 5ER1 5ER2
• 関連するBIRD辞書のPRD_ID: PRD_000266
• 分子名称: ENDOTHIAPEPSIN, INHIBITOR H261, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: aspartic proteinase mechanism, atomic resolution, succinimide, anisotropic refinement, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: CRYPHONECTRIA PARASITICA (CHESTNUT BLIGHT FUNGUS); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35308.45

構造登録者

Coates, L.,Erskine, P.T.,Mall, S.,Gill, R.S.,Wood, S.P.,Myles, D.A.A.,Cooper, J.B. (登録日: 2003-03-31, 公開日: 2003-04-02, 最終更新日: 2023-11-15)

• 主引用文献: Erskine, P.T.,Coates, L.,Mall, S.,Gill, R.S.,Wood, S.P.,Myles, D.A.A.,Cooper, J.B.; Atomic Resolution Analysis of the Catalytic Site of an Aspartic Proteinase and an Unexpected Mode of Binding by Short Peptides; Protein Sci., 12:1741-, 2003; PubMed: 12876323; DOI: 10.1110/PS.0305203

実験手法

X-RAY DIFFRACTION (1.1 Å)