1NBP

Crystal Structure Of Human Interleukin-2 Y31C Covalently Modified At C31 With 3-Mercapto-1-(1,3,4,9-tetrahydro-B-carbolin-2-yl)-propan-1-one

Summary for 1NBP

Entry DOI	10.2210/pdb1nbp/pdb
Related	1M47 1M48 1M49 1M4A 1M4B 1M4C
Descriptor	Interleukin-2, SULFATE ION, 3-MERCAPTO-1-(1,3,4,9-TETRAHYDRO-B-CARBOLIN-2-YL)-PROPAN-1-ONE, ... (4 entities in total)
Functional Keywords	cytokine, four-helix bundle, small molecule complex
Biological source	Homo sapiens (human)
Cellular location	Secreted: P60568
Total number of polymer chains	1
Total formula weight	15732.37
Authors	Hyde, J.,Braisted, A.C.,Randal, M.,Arkin, M.R. (deposition date: 2002-12-03, release date: 2002-12-18, Last modification date: 2023-08-16)
Primary citation	Hyde, J.,Braisted, A.C.,Randal, M.,Arkin, M.R. Discovery and characterization of cooperative ligand binding in the adaptive region of interleukin-2 Biochemistry, 42:6475-6483, 2003 Cited by PubMed: 12767230 DOI: 10.1021/bi034138g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation