1NBP
Crystal Structure Of Human Interleukin-2 Y31C Covalently Modified At C31 With 3-Mercapto-1-(1,3,4,9-tetrahydro-B-carbolin-2-yl)-propan-1-one
Summary for 1NBP
Entry DOI | 10.2210/pdb1nbp/pdb |
Related | 1M47 1M48 1M49 1M4A 1M4B 1M4C |
Descriptor | Interleukin-2, SULFATE ION, 3-MERCAPTO-1-(1,3,4,9-TETRAHYDRO-B-CARBOLIN-2-YL)-PROPAN-1-ONE, ... (4 entities in total) |
Functional Keywords | cytokine, four-helix bundle, small molecule complex |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P60568 |
Total number of polymer chains | 1 |
Total formula weight | 15732.37 |
Authors | Hyde, J.,Braisted, A.C.,Randal, M.,Arkin, M.R. (deposition date: 2002-12-03, release date: 2002-12-18, Last modification date: 2023-08-16) |
Primary citation | Hyde, J.,Braisted, A.C.,Randal, M.,Arkin, M.R. Discovery and characterization of cooperative ligand binding in the adaptive region of interleukin-2 Biochemistry, 42:6475-6483, 2003 Cited by PubMed: 12767230DOI: 10.1021/bi034138g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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