1NBP
Crystal Structure Of Human Interleukin-2 Y31C Covalently Modified At C31 With 3-Mercapto-1-(1,3,4,9-tetrahydro-B-carbolin-2-yl)-propan-1-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-2 | polymer | 133 | 15375.9 | 1 | UniProt (P60568) Pfam (PF00715) | Homo sapiens (human) | IL-2, T-cell growth factor, TCGF, Aldesleukin |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | 3-MERCAPTO-1-(1,3,4,9-TETRAHYDRO-B-CARBOLIN-2-YL)-PROPAN-1-ONE | non-polymer | 260.4 | 1 | Chemie (MHC) | |||
| 4 | D (A) | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A: 1 - 133 (UniProt: P60568)
| PDB | External Database | Details |
|---|---|---|
| Cys 31 | Tyr 51 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15375.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 356.4 | |
| All* | Total formula weight | 15732.4 |
