1E82
Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD59601
Summary for 1E82
Entry DOI | 10.2210/pdb1e82/pdb |
Related | 1E5O 1E80 1E81 1EED 1ENT 1EPL 1EPM 1EPN 1EPO 1EPP 1EPQ 1EPR 1ER8 2ER0 2ER6 2ER7 2ER9 3ER3 3ER5 4APE 4ER1 4ER2 4ER4 5ER1 5ER2 |
Descriptor | ENDOTHIAPEPSIN, (2S)-1-{[(2R)-1-{[(2S,3R)-1-cyclohexyl-3-hydroxy-4-(pyridin-4-yloxy)butan-2-yl]amino}-3-(methylsulfanyl)-1-oxopropan-2-yl]amino}-1-oxo-3-phenylpropan-2-yl 4-aminopiperidine-1-carboxylate (3 entities in total) |
Functional Keywords | acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | ENDOTHIA PARASITICA |
Total number of polymer chains | 1 |
Total formula weight | 34469.70 |
Authors | Read, J.A.,Cooper, J.B.,Toldo, L.,Rippmann, F.,Raddatz, P. (deposition date: 2000-09-15, release date: 2000-10-19, Last modification date: 2023-12-13) |
Primary citation | Read, J.A. Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases. Thesis, 1999 |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report