1DX6

STRUCTURE OF ACETYLCHOLINESTERASE COMPLEXED WITH (-)-GALANTHAMINE AT 2.3A RESOLUTION

Summary for 1DX6

• Entry DOI: 10.2210/pdb1dx6/pdb
• Related: 1ACJ 1ACL 1AMN 1AX9 1CFJ 1EVE 1FSS 1VOT 2ACE 2ACK 3ACE 4ACE
• Descriptor: ACETYLCHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, TETRAETHYLENE GLYCOL, ... (6 entities in total)
• Functional Keywords: hydrolase, serine hydrolase, cholinesterase, alzheimer's disease
• Biological source: TORPEDO CALIFORNICA (PACIFIC ELECTRIC RAY)
• Total number of polymer chains: 1
• Total formula weight: 62673.49

Authors

Greenblatt, H.M.,Kryger, G.,Lewis, T.T.,Silman, I.,Sussman, J.L. (deposition date: 1999-12-21, release date: 2000-01-02, Last modification date: 2023-12-06)

• Primary citation: Greenblatt, H.M.,Kryger, G.,Lewis, T.T.,Silman, I.,Sussman, J.L.; Structure of Acetylcholinesterase Complexed with (-)-Galanthamine at 2.3A Resolution; FEBS Lett., 463:321-, 1999; PubMed: 10606746; DOI: 10.1016/S0014-5793(99)01637-3

Experimental method

X-RAY DIFFRACTION (2.3 Å)