1DGK
MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I WITH GLUCOSE AND ADP IN THE ACTIVE SITE
Summary for 1DGK
Entry DOI | 10.2210/pdb1dgk/pdb |
Related | 1CZA 1HKB 1HKC |
Descriptor | HEXOKINASE TYPE I, alpha-D-glucopyranose, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | brain hexokinase, mammalian hexokinase 1, sugar kinase, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 103866.67 |
Authors | Aleshin, A.E.,Liu, X.,Kirby, C.,Bourenkov, G.P.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B. (deposition date: 1999-11-24, release date: 2000-03-08, Last modification date: 2024-02-07) |
Primary citation | Aleshin, A.E.,Kirby, C.,Liu, X.,Bourenkov, G.P.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B. Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation. J.Mol.Biol., 296:1001-1015, 2000 Cited by PubMed: 10686099DOI: 10.1006/jmbi.1999.3494 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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