1OEC
FGFr2 kinase domain
Summary for 1OEC
Entry DOI | 10.2210/pdb1oec/pdb |
Related | 1DJS 1E0O 1EV2 1GJO 1II4 1IIL |
Descriptor | FIBROBLAST GROWTH FACTOR RECEPTOR 2, SULFATE ION, 4-ARYL-2-PHENYLAMINO PYRIMIDINE, ... (4 entities in total) |
Functional Keywords | transferase, fgfr2 kinase domain, receptor tyrosine kinase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform 14: Secreted. Isoform 19: Secreted: P21802 |
Total number of polymer chains | 1 |
Total formula weight | 36740.70 |
Authors | Ceska, T.A.,Owens, R.,Doyle, C.,Hamlyn, P.,Crabbe, T.,Moffat, D.,Davis, J.,Martin, R.,Perry, M.J. (deposition date: 2003-03-24, release date: 2004-10-27, Last modification date: 2023-12-13) |
Primary citation | Ceska, T.A.,Owens, R.,Doyle, C.,Hamlyn, P.,Crabbe, T.,Moffat, D.,Davis, J.,Martin, R.,Perry, M.J. The Crystal Structure of the Fgfr2 Tyrosine Kinase Domain in Complex with 4-Aryl-2-Phenylamino Pyrimidine Angiogenesis Inhibitors To be Published, |
Experimental method |
Structure validation
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