Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 781 |
Chain | Residue |
A | ARG625 |
A | ARG649 |
A | ARG664 |
A | SO4782 |
A | HOH2159 |
A | HOH2160 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 782 |
Chain | Residue |
A | ARG678 |
A | SO4781 |
A | HOH2159 |
A | HOH2161 |
A | LYS526 |
A | THR661 |
A | GLY663 |
site_id | AC3 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE AA2 A 789 |
Chain | Residue |
A | LEU487 |
A | GLU489 |
A | GLY490 |
A | ALA515 |
A | VAL564 |
A | GLU565 |
A | ALA567 |
A | LEU633 |
A | ASP644 |
A | HOH2011 |
A | HOH2023 |
A | HOH2064 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 31 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGCFGQVVmAeavgidkdkpkeavt...VAVK |
Chain | Residue | Details |
A | LEU487-LYS517 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
Chain | Residue | Details |
A | CYS622-VAL634 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP626 | |
Chain | Residue | Details |
A | LEU487 | |
A | LYS517 | |
A | GLU565 | |
A | ASN571 | |
Chain | Residue | Details |
A | TYR466 | |
A | TYR588 | |
Chain | Residue | Details |
A | TYR586 | |
A | TYR656 | |
A | TYR657 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASP626 | |
A | ARG630 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASP626 | |
A | ALA628 | |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | THR661 | |
A | ASP626 | |
A | ALA628 | |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASP626 | |
A | ALA628 | |
A | ASN631 | |