1NNP

X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-ATPA at 1.9 A resolution. Crystallization without zinc ions.

Summary for 1NNP

• Entry DOI: 10.2210/pdb1nnp/pdb
• Related: 1FTJ 1FTK 1FTL 1FTM 1FTO 1FW0 1GR2 1LB8 1LB9 1LBB 1LBC 1M5B 1M5C 1M5D 1M5E 1M5F 1MM6 1MM7 1MY3 1MY4 1NNK
• Descriptor: Glutamate receptor 2, SULFATE ION, 3-(5-TERT-BUTYL-3-OXIDOISOXAZOL-4-YL)-L-ALANINATE, ... (4 entities in total)
• Functional Keywords: ionotropic glutamate receptor glur2, ligand-binding core, agonist complex., membrane protein
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Cell membrane ; Multi-pass membrane protein : P19491
• Total number of polymer chains: 2
• Total formula weight: 59089.96

Authors

Lunn, M.L.,Hogner, A.,Stensbol, T.B.,Gouaux, E.,Egebjerg, J.,Kastrup, J.S. (deposition date: 2003-01-14, release date: 2003-03-11, Last modification date: 2024-04-03)

• Primary citation: Lunn, M.L.,Hogner, A.,Stensbol, T.B.,Gouaux, E.,Egebjerg, J.,Kastrup, J.S.; Three-Dimensional Structure of the Ligand-Binding Core of GluR2 in Complex with the Agonist (S)-ATPA: Implications for Receptor Subunit Selectivity.; J.Med.Chem., 46:872-875, 2003; PubMed: 12593667; DOI: 10.1021/jm021020+

Experimental method

X-RAY DIFFRACTION (1.9 Å)