1M5C

X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH Br-HIBO AT 1.65 A RESOLUTION

Summary for 1M5C

• Entry DOI: 10.2210/pdb1m5c/pdb
• Related: 1FTJ 1FTK 1FTL 1FTM 1FTO 1FWO 1GR2 1LB8 1LB9 1M5B 1M5D 1M5E 1M5F
• Descriptor: Glutamate receptor 2, (S)-2-AMINO-3-(4-BROMO-3-HYDROXY-ISOXAZOL-5-YL)PROPIONIC ACID (3 entities in total)
• Functional Keywords: ionotropic glutamate receptor, glur2, ligand binding core, agonist complex, membrane protein
• Biological source: Rattus norvegicus (Norway rat); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P19491
• Total number of polymer chains: 1
• Total formula weight: 29472.72

Authors

Hogner, A.,Kastrup, J.S.,Jin, R.,Liljefors, T.,Mayer, M.L.,Egebjerg, J.,Larsen, I.K.,Gouaux, E. (deposition date: 2002-07-09, release date: 2002-09-18, Last modification date: 2017-08-16)

• Primary citation: Hogner, A.,Kastrup, J.S.,Jin, R.,Liljefors, T.,Mayer, M.L.,Egebjerg, J.,Larsen, I.K.,Gouaux, E.; Structural Basis for AMPA Receptor Activation and Ligand Selectivity: Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding Core; J.Mol.Biol., 322:93-109, 2002; PubMed: 12215417; DOI: 10.1016/S0022-2836(02)00650-2

Experimental method

X-RAY DIFFRACTION (1.65 Å)