Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1006 |
| Chain | Residue |
| B | ASP136 |
| B | SER137 |
| B | LYS141 |
| B | ARG145 |
| B | HOH1027 |
| B | HOH1172 |
| B | HOH1211 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1007 |
| Chain | Residue |
| A | ARG145 |
| A | HOH1051 |
| A | HOH1066 |
| A | HOH1103 |
| A | SER137 |
| A | LYS141 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CE2 A 1008 |
| Chain | Residue |
| A | GLU10 |
| A | TYR58 |
| A | PRO86 |
| A | LEU87 |
| A | THR88 |
| A | ARG93 |
| A | GLY138 |
| A | SER139 |
| A | THR140 |
| A | THR171 |
| A | GLU190 |
| A | MET193 |
| A | TYR217 |
| A | HOH1038 |
| A | HOH1056 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CE2 B 1007 |
| Chain | Residue |
| B | GLU10 |
| B | TYR58 |
| B | PRO86 |
| B | LEU87 |
| B | THR88 |
| B | ARG93 |
| B | GLY138 |
| B | SER139 |
| B | THR140 |
| B | THR171 |
| B | GLU190 |
| B | MET193 |
| B | HOH1023 |
| B | HOH1091 |
| B | HOH1242 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PRO86 | |
| A | THR88 | |
| A | ARG93 | |
| B | SER139 | |
| B | THR140 | |
| B | GLU190 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG61 | |
| B | ARG145 | |
| B | LYS237 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| B | ILE118 | |
| Chain | Residue | Details |
| B | SER147 | |
| Chain | Residue | Details |
| B | SER181 | |
