1MS7
X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-Des-Me-AMPA at 1.97 A resolution, Crystallization in the presence of zinc acetate
Summary for 1MS7
Entry DOI | 10.2210/pdb1ms7/pdb |
Related | 1FTJ 1FTK 1FTL 1FTM 1FTO 1FWO 1GR2 1LB8 1LB9 1LBB 1LBC 1M5B 1M5C 1M5D 1M5E 1M5F 1MM6 1MM7 |
Descriptor | Glutamate receptor subunit 2, ZINC ION, (S)-2-AMINO-3-(3-HYDROXY-ISOXAZOL-4-YL)PROPIONIC ACID, ... (4 entities in total) |
Functional Keywords | ionotropic glutamate receptor glur2, ligand-binding core, agonist complex, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 3 |
Total formula weight | 88573.92 |
Authors | Kasper, C.,Lunn, M.-L.,Liljefors, T.,Gouaux, E.,Egebjerg, J.,Kastrup, J.S. (deposition date: 2002-09-19, release date: 2003-07-08, Last modification date: 2023-10-25) |
Primary citation | Kasper, C.,Lunn, M.-L.,Liljefors, T.,Gouaux, E.,Egebjerg, J.,Kastrup, J.S. GluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists FEBS Lett., 531:173-178, 2002 Cited by PubMed: 12417307DOI: 10.1016/S0014-5793(02)03496-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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