1MS7
X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-Des-Me-AMPA at 1.97 A resolution, Crystallization in the presence of zinc acetate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glutamate receptor subunit 2 | polymer | 263 | 29221.7 | 3 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR2 |
| 2 | D, E, G, H, I... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | F, K, L (A, B, C) | (S)-2-AMINO-3-(3-HYDROXY-ISOXAZOL-4-YL)PROPIONIC ACID | non-polymer | 172.1 | 3 | Chemie (SHI) | |||
| 4 | M, N, O (A, B, C) | water | water | 18.0 | 1166 | Chemie (HOH) |
Sequence modifications
A, B, C: 0 - 114 (UniProt: P19491)
A, B, C: 117 - 260 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Ala -1 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 115 | - | linker |
| Thr 116 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87665.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 908.9 | |
| All* | Total formula weight | 88573.9 |
