6DGQ
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with CAY10506
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peroxisome proliferator-activated receptor gamma | polymer | 276 | 31506.6 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | A | N-(2-{4-[(2,4-dioxo-3,4-dihydro-2H-1lambda~4~,3-thiazol-5-yl)methyl]phenoxy}ethyl)-5-[(3R)-1,2-dithiolan-3-yl]pentanamide | non-polymer | 454.6 | 1 | Chemie (GBV) | |||
| 3 | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, B: 203 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63013.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 454.6 | |
| All* | Total formula weight | 63467.8 |
