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6DGQ

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with CAY10506

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues13
Detailsbinding site for residue GBV A 501
ChainResidue
APHE282
ALEU453
ALEU469
ATYR473
AHOH671
AGLY284
ACYS285
ASER289
AHIS323
ALEU330
AILE341
AMET364
AHIS449

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
ChainResidueDetails
AGLN286
AHIS323
AHIS449
ATYR473
BGLN286
BHIS323
BHIS449
BTYR473

217705

PDB entries from 2024-03-27

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