3PD8
X-ray structure of the ligand-binding core of GluA2 in complex with (S)-7-HPCA at 2.5 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glutamate receptor 2 | polymer | 261 | 29077.6 | 3 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (brown rat rat rats) | GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2 |
| 2 | D, H, I, K, L (A, B, C) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 3 | E, J, M (A, B, C) | (7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-7-carboxylic acid | non-polymer | 184.1 | 3 | Chemie (HA7) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | G (A) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 6 | N (C) | CACODYLATE ION | non-polymer | 137.0 | 1 | Chemie (CAC) | |||
| 7 | O, P, Q (A, B, C) | water | water | 18.0 | 396 | Chemie (HOH) |
Sequence modifications
A, B, C: 0 - 114 (UniProt: P19491)
A, B, C: 117 - 259 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Ala -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 115 | - | linker |
| Thr 116 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87232.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1168.6 | |
| All* | Total formula weight | 88401.3 |
