3PD8
X-ray structure of the ligand-binding core of GluA2 in complex with (S)-7-HPCA at 2.5 A resolution
Summary for 3PD8
Entry DOI | 10.2210/pdb3pd8/pdb |
Related | 1M5E 3PD9 |
Descriptor | Glutamate receptor 2, ZINC ION, (7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-7-carboxylic acid, ... (7 entities in total) |
Functional Keywords | ionotropic glutamate receptor glua2, ligand-binding core, agonist complex, membrane protein |
Biological source | Rattus norvegicus (brown rat,rat,rats) More |
Total number of polymer chains | 3 |
Total formula weight | 88401.29 |
Authors | Frydenvang, K.,Kastrup, J.S. (deposition date: 2010-10-22, release date: 2010-12-29, Last modification date: 2023-09-06) |
Primary citation | Frydenvang, K.,Pickering, D.S.,Greenwood, J.R.,Krogsgaard-Larsen, N.,Brehm, L.,Nielsen, B.,Vogensen, S.B.,Hald, H.,Kastrup, J.S.,Krogsgaard-Larsen, P.,Clausen, R.P. Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid. J. Med. Chem., 53:8354-8361, 2010 Cited by PubMed: 21067182DOI: 10.1021/jm101218a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.476 Å) |
Structure validation
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