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8Y6K	Cryo-EM structure of full-length MICAL1 in the autoinhibited state Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, ZINC ION, [F-actin]-monooxygenase MICAL1 Authors: Niu, F, Wei, Z. Deposit date: 2024-02-02 Release date: 2024-08-28 Method: ELECTRON MICROSCOPY (3.94 Å) Cite: Autoinhibition and relief mechanisms for MICAL monooxygenases in F-actin disassembly. Nat Commun, 15, 2024
8RO0	Structure of the C. elegans Intron Lariat Spliceosome primed for disassembly (ILS') Descriptor: Cell division cycle 5-like protein, Coiled-coil domain-containing protein 12, GCF C-terminal domain-containing protein, ... Authors: Vorlaender, M.K, Rothe, P, Plaschka, C. Deposit date: 2024-01-11 Release date: 2024-08-07 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Mechanism for the initiation of spliceosome disassembly. Nature, 632, 2024
8RO1	Structure of the C. elegans Intron Lariat Spliceosome double-primed for disassembly (ILS'') Descriptor: CWF19-like protein 1 homolog, CWF19-like protein 2 homolog, Cell division cycle 5-like protein, ... Authors: Vorlaender, M.K, Rothe, P, Plaschka, C. Deposit date: 2024-01-11 Release date: 2024-08-07 Last modified: 2024-08-21 Method: ELECTRON MICROSCOPY (3 Å) Cite: Mechanism for the initiation of spliceosome disassembly. Nature, 632, 2024
8I0T	The cryo-EM structure of human Bact-III complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (3 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0P	The cryo-EM structure of human pre-Bact complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0V	The cryo-EM structure of human post-Bact complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (3 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0U	The cryo-EM structure of human Bact-IV complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0R	The cryo-EM structure of human Bact-I complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (3 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0S	The cryo-EM structure of human Bact-II complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0W	The cryo-EM structure of human C complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2023-01-11 Release date: 2024-07-31 Last modified: 2024-08-07 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8K3Z	Cryo-EM structure of CXCR4 in complex with CXCL12 Descriptor: C-X-C chemokine receptor type 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Liu, Y.Z, Liu, A.J, Liao, Q.W, Ye, R.D. Deposit date: 2023-07-17 Release date: 2024-07-17 Method: ELECTRON MICROSCOPY (2.81 Å) Cite: Cryo-EM structure of CXCR4 in complex with CXCL12 To Be Published
8TAV	FphH, Staphylococcus aureus fluorophosphonate-binding serine hydrolases H, boronic acid-based compound N34 bound Descriptor: CALCIUM ION, Fluorophosphonate-binding serine hydrolase H, [5-(trifluoromethyl)thiophen-2-yl]boronic acid Authors: Fellner, M. Deposit date: 2023-06-28 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (1.39 Å) Cite: FphH, Staphylococcus aureus fluorophosphonate-binding serine hydrolases H, boronic acid-based compound N34 bound To Be Published
9FMD	Integrative model of the human post-catalytic spliceosome (P-complex) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Rothe, P, Plaschka, C, Vorlaender, M.K. Deposit date: 2024-06-05 Release date: 2024-07-10 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Mechanism for the initiation of spliceosome disassembly. Nature, 2024
8SO8	Crystal structure of an N-terminally truncated variant of Escherichia coli RapA Descriptor: CHLORIDE ION, RNA polymerase-associated protein RapA, SULFATE ION Authors: Shaw, G.X, Kakar, S, Ji, X. Deposit date: 2023-04-28 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (2.607 Å) Cite: Crystal structure of an N-terminally truncated variant of Escherichia coli RapA To be published
8SP4	Crystal structure of N-terminally truncated Escherichia coli RapA in complex with ATP-gamma-S Descriptor: CHLORIDE ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, RNA polymerase-associated protein RapA Authors: Shaw, G.X, Kakar, S, Ji, X. Deposit date: 2023-05-02 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (2.401 Å) Cite: Crystal structure of N-terminally truncated Escherichia coli RapA in complex with ATP-gamma-S To be published
8SPG	Crystal structure of N-terminally truncated Escherichia coli RapA in complex with MgADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... Authors: Shaw, G.X, Ji, X. Deposit date: 2023-05-03 Release date: 2024-07-03 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of N-terminally truncated Escherichia coli RapA in complex with MgADP To be published
8YAX	SARS-CoV-2 DMV nsp3-4 pore complex (full-pore) Descriptor: Non-structural protein 4, Papain-like protease nsp3 Authors: Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T. Deposit date: 2024-02-10 Release date: 2024-06-19 Last modified: 2024-09-18 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: Molecular architecture of coronavirus double-membrane vesicle pore complex. Nature, 633, 2024
8YB7	SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C3 symmetry) Descriptor: Non-structural protein 4, Papain-like protease nsp3 Authors: Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T. Deposit date: 2024-02-12 Release date: 2024-06-19 Last modified: 2024-09-18 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Molecular architecture of coronavirus double-membrane vesicle pore complex. Nature, 633, 2024
8YB5	SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C6 symmetry) Descriptor: Non-structural protein 4, Papain-like protease nsp3 Authors: Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T. Deposit date: 2024-02-11 Release date: 2024-06-19 Last modified: 2024-09-18 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Molecular architecture of coronavirus double-membrane vesicle pore complex. Nature, 633, 2024
8QPA	Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-01 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8R0B	Cryo-EM structure of the cross-exon pre-B+ATP complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-31 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8QPK	Cryo-EM Structure of Pre-B+5'ss Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-02 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8R09	Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-31 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8QOZ	Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss RNA oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-09-29 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8QP8	Cryo-EM Structure of Pre-B Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Pre-mRNA-processing factor 6, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-09-30 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024

 

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