1IUY
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SOLUTION STRUCTURE OF THE CULLIN-3 HOMOLOGUE
Descriptor:cullin-3 homologue
Authors:Inoue, M., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-03-08
Release date:2003-10-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the cullin-3 homologue
To be published
2DO7
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SOLUTION STRUCTURE OF THE WINGED HELIX-TURN-HELIX MOTIF OF HUMAN CUL-4B
Descriptor:Cullin-4B
Authors:Suzuki, S., Muto, Y., Inoue, M., Kigawa, T., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-27
Release date:2007-04-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the winged helix-turn-helix motif of human CUL-4B
To be Published
1LDK
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STRUCTURE OF THE CUL1-RBX1-SKP1-F BOXSKP2 SCF UBIQUITIN LIGASE COMPLEX
Descriptor:CULLIN HOMOLOG, ring-box protein 1, CYCLIN A/CDK2-ASSOCIATED PROTEIN P19, ...
Authors:Zheng, N., Schulman, B.A., Song, L., Miller, J.J., Jeffrey, P.D., Wang, P., Chu, C., Koepp, D.M., Elledge, S.J., Pagano, M., Conaway, R.C., Conaway, J.W., Harper, J.W., Pavletich, N.P.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
3DPL
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STRUCTURAL INSIGHTS INTO NEDD8 ACTIVATION OF CULLIN-RING LIGASES: CONFORMATIONAL CONTROL OF CONJUGATION.
Descriptor:Cullin-5, RING-box protein 1, ZINC ION
Authors:Duda, D.M., Schulman, B.A.
Deposit date:2008-07-08
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134, 2008
3RTR
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A RING E3-SUBSTRATE COMPLEX POISED FOR UBIQUITIN-LIKE PROTEIN TRANSFER: STRUCTURAL INSIGHTS INTO CULLIN-RING LIGASES
Descriptor:Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION
Authors:Calabrese, M.F., Scott, D.C., Duda, D.M., Grace, C.R., Kurinov, I., Kriwacki, R.W., Schulman, B.A.
Deposit date:2011-05-03
Release date:2011-07-20
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases.
Nat.Struct.Mol.Biol., 18, 2011
4P5O
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STRUCTURE OF AN RBX1-UBC12~NEDD8-CUL1-DCN1 COMPLEX: A RING-E3-E2~UBIQUITIN-LIKE PROTEIN-SUBSTRATE INTERMEDIATE TRAPPED IN ACTION
Descriptor:Cullin-1, E3 ubiquitin-protein ligase RBX1, DCN1-like protein 1, ...
Authors:Scott, D.C., Schulman, B.A.
Deposit date:2014-03-18
Release date:2014-07-02
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.1071 Å)
Cite:Structure of a RING E3 Trapped in Action Reveals Ligation Mechanism for the Ubiquitin-like Protein NEDD8.
Cell, 157, 2014
1LDJ
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STRUCTURE OF THE CUL1-RBX1-SKP1-F BOXSKP2 SCF UBIQUITIN LIGASE COMPLEX
Descriptor:Cullin homolog 1, ring-box protein 1, ZINC ION
Authors:Zheng, N., Schulman, B.A., Song, L., Miller, J.J., Jeffrey, P.D., Wang, P., Chu, C., Koepp, D.M., Elledge, S.J., Pagano, M., Conaway, R.C., Conaway, J.W., Harper, J.W., Pavletich, N.P.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
1U6G
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CRYSTAL STRUCTURE OF THE CAND1-CUL1-ROC1 COMPLEX
Descriptor:Cullin homolog 1, RING-box protein 1, TIP120 protein, ...
Authors:Goldenberg, S.J., Shumway, S.D., Cascio, T.C., Garbutt, K.C., Liu, J., Xiong, Y., Zheng, N.
Deposit date:2004-07-29
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases
Cell(Cambridge,Mass.), 119, 2004
2HYE
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CRYSTAL STRUCTURE OF THE DDB1-CUL4A-RBX1-SV5V COMPLEX
Descriptor:DNA damage-binding protein 1, Nonstructural protein V, Cullin-4A, ...
Authors:Angers, S., Li, T., Yi, X., MacCoss, M.J., Moon, R.T., Zheng, N.
Deposit date:2006-08-05
Release date:2006-10-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.
Nature, 443, 2006
3DQV
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STRUCTURAL INSIGHTS INTO NEDD8 ACTIVATION OF CULLIN-RING LIGASES: CONFORMATIONAL CONTROL OF CONJUGATION
Descriptor:NEDD8, Cullin-5, Rbx1, ...
Authors:Duda, D.M., Borg, L.A., Scott, D.C., Hunt, H.W., Hammel, M., Schulman, B.A.
Deposit date:2008-07-09
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134, 2008
3O2P
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A DUAL E3 MECHANISM FOR RUB1 LIGATION TO CDC53: DCN1(P)-CDC53(WHB)
Descriptor:Defective in cullin neddylation protein 1, Cell division control protein 53, GLYCEROL
Authors:Scott, D.C., Monda, J.K., Grace, C.R.R., Duda, D.M., Kriwacki, R.W., Kurz, T., Schulman, B.A.
Deposit date:2010-07-22
Release date:2010-09-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.233 Å)
Cite:A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
3O6B
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A DUAL E3 MECHANISM FOR RUB1 LIGATION TO CDC53: DCN1(P)-CDC53(WHB) LOW RESOLUTION
Descriptor:Defective in cullin neddylation protein 1, Cell division control protein 53
Authors:Scott, D.C., Monda, J.K., Grace, C.R.R., Duda, D.M., Kriwacki, R.W., Kurz, T., Schulman, B.A.
Deposit date:2010-07-28
Release date:2010-09-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
3TDU
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N-TERMINAL ACETYLATION ACTS AS AN AVIDITY ENHANCER WITHIN AN INTERCONNECTED MULTIPROTEIN COMPLEX: STRUCTURE OF A HUMAN CUL1WHB-DCN1P-ACETYLATED UBC12N COMPLEX
Descriptor:DCN1-like protein 1, Cullin-1, NEDD8-conjugating enzyme Ubc12
Authors:Scott, D.C., Monda, J.K., Bennett, E.J., Harper, J.W., Schulman, B.A.
Deposit date:2011-08-11
Release date:2011-10-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.
Science, 334, 2011
3TDZ
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N-TERMINAL ACETYLATION ACTS AS AN AVIDITY ENHANCER WITHIN AN INTERCONNECTED MULTIPROTEIN COMPLEX: STRUCTURE OF A HUMAN CUL1WHB-DCN1P-STAPLED ACETYLATED UBC12N COMPLEX
Descriptor:DCN1-like protein 1, Cullin-1, STAPLED PEPTIDE
Authors:Scott, D.C., Monda, J.K., Bennett, E.J., Harper, J.W., Schulman, B.A.
Deposit date:2011-08-11
Release date:2011-10-12
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.
Science, 334, 2011
4A0C
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STRUCTURE OF THE CAND1-CUL4B-RBX1 COMPLEX
Descriptor:CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1, CULLIN-4B, E3 UBIQUITIN-PROTEIN LIGASE RBX1, ...
Authors:Scrima, A., Fischer, E.S., Faty, M., Gut, H., Thoma, N.H.
Deposit date:2011-09-08
Release date:2011-11-30
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
Cell(Cambridge,Mass.), 147, 2011
4A0K
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STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX
Descriptor:CULLIN-4A, E3 UBIQUITIN-PROTEIN LIGASE RBX1, DNA DAMAGE-BINDING PROTEIN 1, ...
Authors:Fischer, E.S., Scrima, A., Gut, H., Thoma, N.H.
Deposit date:2011-09-09
Release date:2011-12-14
Method:X-RAY DIFFRACTION (5.93 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
4A0L
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STRUCTURE OF DDB1-DDB2-CUL4B-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX
Descriptor:DNA DAMAGE-BINDING PROTEIN 1, DNA DAMAGE-BINDING PROTEIN 2, CULLIN-4B, ...
Authors:Fischer, E.S., Scrima, A., Gut, H., Thoma, N.H.
Deposit date:2011-09-09
Release date:2011-12-14
Last modified:2012-11-07
Method:X-RAY DIFFRACTION (7.4 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
5N4W
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CRYSTAL STRUCTURE OF THE CUL2-RBX1-ELOBC-VHL UBIQUITIN LIGASE COMPLEX
Descriptor:Cullin-2, Von Hippel-Lindau disease tumor suppressor, E3 ubiquitin-protein ligase RBX1, ...
Authors:Cardote, T.A.F., Gadd, M.S., Ciulli, A.
Deposit date:2017-02-11
Release date:2017-06-07
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex.
Structure, 25, 2017
5V89
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STRUCTURE OF DCN4 PONY DOMAIN BOUND TO CUL1 WHB
Descriptor:DCN1-like protein 4, Cullin-1
Authors:Guy, R.K., Schulman, B.A., Scott, D.C., Hammill, J.T.
Deposit date:2017-03-21
Release date:2017-05-24
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.
Nat. Chem. Biol., 13, 2017
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