5V89

Structure of DCN4 PONY domain bound to CUL1 WHB

Summary for 5V89

Entry DOI	10.2210/pdb5v89/pdb
Related	5V83 5V86 5V88
Descriptor	DCN1-like protein 4, Cullin-1 (3 entities in total)
Functional Keywords	e3 ligase, ligase - protein binding complex, ligase / protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	31772.53
Authors	Guy, R.K.,Schulman, B.A.,Scott, D.C.,Hammill, J.T. (deposition date: 2017-03-21, release date: 2017-05-24, Last modification date: 2023-10-04)
Primary citation	Scott, D.C.,Hammill, J.T.,Min, J.,Rhee, D.Y.,Connelly, M.,Sviderskiy, V.O.,Bhasin, D.,Chen, Y.,Ong, S.S.,Chai, S.C.,Goktug, A.N.,Huang, G.,Monda, J.K.,Low, J.,Kim, H.S.,Paulo, J.A.,Cannon, J.R.,Shelat, A.A.,Chen, T.,Kelsall, I.R.,Alpi, A.F.,Pagala, V.,Wang, X.,Peng, J.,Singh, B.,Harper, J.W.,Schulman, B.A.,Guy, R.K. Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. Nat. Chem. Biol., 13:850-857, 2017 Cited by PubMed: 28581483 DOI: 10.1038/nchembio.2386 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation