PDB: 90 resultsInfo pagesStatus searchChemie searchBIRD

---

7QXX	Proteasome-ZFAND5 Complex Z+E state Descriptor: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QY7	Proteasome-ZFAND5 Complex Z-A state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QXN	Proteasome-ZFAND5 Complex Z+A state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-26 Release date: 2023-02-08 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QXP	Proteasome-ZFAND5 Complex Z+B state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-26 Release date: 2023-02-08 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QYB	Proteasome-ZFAND5 Complex Z-C state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QXU	Proteasome-ZFAND5 Complex Z+C state Descriptor: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QXW	Proteasome-ZFAND5 Complex Z+D state Descriptor: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
7QYA	Proteasome-ZFAND5 Complex Z-B state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
8CVT	Human 19S-20S proteasome, state SD2 Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Zhao, J. Deposit date: 2022-05-18 Release date: 2022-11-02 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
7EWF	Selenomethionine-substituted structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1 Descriptor: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3 Authors: Kuang, Z, Niu, L. Deposit date: 2021-05-25 Release date: 2022-09-07 Last modified: 2023-04-05 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing. Nucleic Acids Res., 50, 2022
7EWM	Native crystal structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1 Descriptor: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3 Authors: Kuang, Z, Niu, L. Deposit date: 2021-05-25 Release date: 2022-09-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing. Nucleic Acids Res., 50, 2022
7W3M	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD5_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-18 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3I	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-18 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3B	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3G	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3J	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SC_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3A	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED4_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3C	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W37	Structure of USP14-bound human 26S proteasome in state EA1_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3F	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3K	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W38	Structure of USP14-bound human 26S proteasome in state EA2.0_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3H	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W39	Structure of USP14-bound human 26S proteasome in state EA2.1_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7QO3	Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid) Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit RPN10, ... Authors: Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D. Deposit date: 2021-12-23 Release date: 2022-04-13 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13, 2022

 

1234>