1PN5
| NMR structure of the NALP1 Pyrin domain (PYD) | Descriptor: | NACHT-, LRR- and PYD-containing protein 2 | Authors: | Hiller, S, Kohl, A, Fiorito, F, Herrmann, T, Wider, G, Tschopp, J, Grutter, M.G, Wuthrich, K. | Deposit date: | 2003-06-12 | Release date: | 2003-10-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain Structure, 11, 2003
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1UCP
| NMR structure of the PYRIN domain of human ASC | Descriptor: | Apoptosis-associated speck-like protein containing a CARD | Authors: | Liepinsh, E, Barbals, R, Dahl, E, Sharipo, A, Staub, E, Otting, G. | Deposit date: | 2003-04-16 | Release date: | 2003-11-04 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition J.Mol.Biol., 332, 2003
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2DBG
| Solution structure of the Pyrin (PAAD-DAPIN) domain in human Myeloid cell nuclear differentiation antigen | Descriptor: | Myeloid cell nuclear differentiation antigen | Authors: | Saito, K, Inoue, M, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-12-15 | Release date: | 2006-06-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the Pyrin (PAAD-DAPIN) domain in human Myeloid cell nuclear differentiation antigen To be Published
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2HM2
| Solution structure of ASC2 | Descriptor: | Pyrin-only protein 1 | Authors: | Natarajan, A, Ghose, R, Hill, J.M. | Deposit date: | 2006-07-11 | Release date: | 2006-07-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure and dynamics of ASC2, a pyrin domain-only protein that regulates inflammatory signaling J.Biol.Chem., 281, 2006
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2DO9
| Solution structure of the Pyrin/PAAD-DAPIN domain in mouse NALP10 (NACHT, leucine rich repeat and PYD containing 10) | Descriptor: | NACHT-, LRR- and PYD-containing protein 10 | Authors: | Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-28 | Release date: | 2006-10-28 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the Pyrin/PAAD-DAPIN domain in mouse NALP10 (NACHT, leucine rich repeat and PYD containing 10) To be Published
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2YU0
| Solution structures of the PAAD_DAPIN domain of mus musculus interferon-activatable protein 205 | Descriptor: | Interferon-activable protein 205 | Authors: | Sato, M, Tochio, N, Koshiba, S, Watanabe, M, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2008-02-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures of the PAAD_DAPIN domain of mus musculus interferon-activatable protein 205 To be Published
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2KN6
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2KM6
| NMR structure of the NLRP7 Pyrin domain | Descriptor: | NACHT, LRR and PYD domains-containing protein 7 | Authors: | Pinheiro, A, Proell, M, Schwarzenbacher, R, Peti, W. | Deposit date: | 2009-07-21 | Release date: | 2010-06-09 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of the NLRP7 pyrin domain: insight into pyrin-pyrin-mediated effector domain signaling in innate immunity. J.Biol.Chem., 285, 2010
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3QF2
| Crystal structure of NALP3 PYD | Descriptor: | NACHT, LRR and PYD domains-containing protein 3 | Authors: | Park, H.H, Bae, J.Y. | Deposit date: | 2011-01-21 | Release date: | 2011-08-31 | Last modified: | 2011-11-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly J.Biol.Chem., 286, 2011
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2L6A
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4EWI
| Crystal structure of the NLRP4 Pyrin domain | Descriptor: | CHLORIDE ION, NACHT, LRR and PYD domains-containing protein 4, ... | Authors: | Eibl, C, Hessenberger, M, Puehringer, S, Page, R, Diederichs, K, Peti, W. | Deposit date: | 2012-04-27 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural and Functional Analysis of the NLRP4 Pyrin Domain. Biochemistry, 51, 2012
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3VD8
| Crystal structure of human AIM2 PYD domain with MBP fusion | Descriptor: | 1,2-ETHANEDIOL, Maltose-binding periplasmic protein, Interferon-inducible protein AIM2, ... | Authors: | Jin, T.C, Perry, A, Smith, P, Xiao, T.S. | Deposit date: | 2012-01-04 | Release date: | 2013-01-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.0685 Å) | Cite: | Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly. J.Biol.Chem., 288, 2013
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2M5V
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4O7Q
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3J63
| Unified assembly mechanism of ASC-dependent inflammasomes | Descriptor: | Apoptosis-associated speck-like protein containing a CARD | Authors: | Lu, A, Magupalli, V.G, Ruan, J, Yin, Q, Atianand, M.K, Vos, M, Schroder, G.F, Fitzgerald, K.A, Wu, H, Egelman, E.H. | Deposit date: | 2013-12-05 | Release date: | 2014-03-26 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes. Cell(Cambridge,Mass.), 156, 2014
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4N1L
| Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | Descriptor: | NACHT, LRR and PYD domains-containing protein 14 | Authors: | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | Deposit date: | 2013-10-04 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.986 Å) | Cite: | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
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4N1K
| Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | Descriptor: | NACHT, LRR and PYD domains-containing protein 14 | Authors: | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | Deposit date: | 2013-10-04 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
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4N1J
| Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | Descriptor: | GLYCEROL, NACHT, LRR and PYD domains-containing protein 14 | Authors: | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | Deposit date: | 2013-10-04 | Release date: | 2014-07-16 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
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2MPC
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2N00
| NMR Solution structure of AIM2 PYD from Mus musculus | Descriptor: | Interferon-inducible protein AIM2 | Authors: | Hou, X, Niu, X. | Deposit date: | 2015-03-01 | Release date: | 2015-05-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The NMR solution structure of AIM2 PYD domain from Mus musculus reveals a distinct alpha 2-alpha 3 helix conformation from its human homologues Biochem.Biophys.Res.Commun., 461, 2015
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2N1F
| Structure and assembly of the mouse ASC filament by combined NMR spectroscopy and cryo-electron microscopy | Descriptor: | Apoptosis-associated speck-like protein | Authors: | Sborgi, L, Ravotti, F, Dandey, V, Dick, M, Mazur, A, Reckel, S, Chami, M, Scherer, S, Bockmann, A, Egelman, E, Stahlberg, H, Broz, P, Meier, B, Hiller, S. | Deposit date: | 2015-04-01 | Release date: | 2015-10-14 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR | Cite: | Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy. Proc.Natl.Acad.Sci.USA, 112, 2015
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4QOB
| Crystal structure of cPOP1 | Descriptor: | Pyrin domain-containing protein 1 | Authors: | Park, H.H. | Deposit date: | 2014-06-19 | Release date: | 2015-11-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of cPOP1 To be Published
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2NAQ
| 3D NMR solution structure of NLRP3 PYD | Descriptor: | NACHT, LRR and PYD domains-containing protein 3 | Authors: | de Alba, E, Oroz, J. | Deposit date: | 2016-01-07 | Release date: | 2016-07-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | ASC Pyrin Domain Self-associates and Binds NLRP3 Protein Using Equivalent Binding Interfaces. J.Biol.Chem., 291, 2016
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5WPZ
| Crystal structure of MNDA PYD with MBP tag | Descriptor: | MBP-hMNDA-PYD, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Jin, T.C, Xiao, T.S. | Deposit date: | 2016-11-22 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design of an expression system to enhance MBP-mediated crystallization Sci Rep, 7, 2017
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5H7N
| Crystal structure of human NLRP12-PYD with a MBP tag | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NLRP12-PYD with MBP tag, ... | Authors: | Jin, T.C, Xiao, T.S. | Deposit date: | 2016-11-19 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.849 Å) | Cite: | Design of an expression system to enhance MBP-mediated crystallization Sci Rep, 7, 2017
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