4Z80
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8G6B
| Crystal structure of PfAMA1-RON2L chimera | Descriptor: | Apical membrane antigen 1, rhoptry neck protein 2 chimera, SULFATE ION | Authors: | Boulanger, M.J, Ramaswamy, R. | Deposit date: | 2023-02-14 | Release date: | 2023-09-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure guided mimicry of an essential P. falciparum receptor-ligand complex enhances cross neutralizing antibodies. Nat Commun, 14, 2023
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6N87
| Plasmodium falciparum FVO apical membrane antigen 1 (AMA1) bound to MTSL spin-labelled cyclised RON2 peptide | Descriptor: | Apical membrane antigen-1, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, backbone-cyclised peptide bcRON2hp | Authors: | McGowan, S, Drinkwater, N. | Deposit date: | 2018-11-28 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.588 Å) | Cite: | Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe. ChemMedChem, 14, 2019
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4R1B
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3SRI
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4R19
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8GID
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1W8K
| Crystal structure of apical membrane antigen 1 from Plasmodium vivax | Descriptor: | APICAL MEMBRANE ANTIGEN 1, IMIDAZOLE | Authors: | Pizarro, J.C, Vulliez-Le Normand, B, Chesne-Seck, M.-L, Kocken, C.H.M, Thomas, A.W, Bentley, G.A. | Deposit date: | 2004-09-23 | Release date: | 2005-03-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the Malaria Vaccine Candidate Apical Membrane Antigen 1 Science, 308, 2005
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8GIE
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4Z0E
| Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038TRN] peptide | Descriptor: | Apical membrane antigen 1, Rhoptry neck protein 2 | Authors: | Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J. | Deposit date: | 2015-03-26 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction. J.Mol.Biol., 428, 2016
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5NQF
| Crystal structure of Plasmodium falciparum AMA1 in complex with a 39 aa PvRON2 peptide | Descriptor: | Apical membrane antigen 1, Rhoptry neck protein 2 | Authors: | Vulliez-le Normand, B, Saul, F.A, Faber, B.W, Bentley, G.A. | Deposit date: | 2017-04-20 | Release date: | 2017-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cross-reactivity between apical membrane antgen 1 and rhoptry neck protein 2 in P. vivax and P. falciparum: A structural and binding study. PLoS ONE, 12, 2017
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1Z40
| AMA1 from Plasmodium falciparum | Descriptor: | CHLORIDE ION, apical membrane antigen 1 precursor | Authors: | Bai, T, Becker, M, Gupta, A, Strike, P, Murphy, V.J, Anders, R.F, Batchelor, A.H. | Deposit date: | 2005-03-14 | Release date: | 2005-08-16 | Last modified: | 2018-02-14 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Structure of AMA1 from Plasmodium falciparum reveals a clustering of polymorphisms that surround a conserved hydrophobic pocket Proc.Natl.Acad.Sci.Usa, 102, 2005
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4YIV
| Crystal structure of engineered TgAMA1 lacking the DII loop | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Apical membrane antigen AMA1, CADMIUM ION, ... | Authors: | Parker, M.L, Boulanger, M.J. | Deposit date: | 2015-03-02 | Release date: | 2015-05-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity. Plos One, 10, 2015
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2Y8T
| Co-structure of AMA1 with a surface exposed region of RON2 from Toxoplasma gondii | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, APICAL MEMBRANE ANTIGEN, PUTATIVE, ... | Authors: | Tonkin, M.L, Roques, M, Lamarque, M.H, Pugniere, M, Douguet, D, Crawford, J, Lebrun, M, Boulanger, M.J. | Deposit date: | 2011-02-10 | Release date: | 2011-08-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of Ama1 with a Ron2 Peptide Science, 333, 2011
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4R1A
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4R1C
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2X2Z
| Crystal structure AMA1 from Toxoplasma gondii | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, APICAL MEMBRANE ANTIGEN 1, PUTATIVE, ... | Authors: | Crawford, J, Tonkin, M.L, Grujic, O, Boulanger, M.J. | Deposit date: | 2010-01-18 | Release date: | 2010-03-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Characterization of Apical Membrane Antigen 1 (Ama1) from Toxoplasma Gondii. J.Biol.Chem., 285, 2010
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4Z09
| Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Thr2040Ala] peptide | Descriptor: | Apical membrane antigen 1, GLYCEROL, Rhoptry neck protein 2 | Authors: | Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J. | Deposit date: | 2015-03-26 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction. J.Mol.Biol., 428, 2016
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1W81
| Crystal structure of apical membrane antigen 1 from Plasmodium vivax | Descriptor: | APICAL MEMBRANE ANTIGEN 1, IMIDAZOLE | Authors: | Pizarro, J.C, Vulliez-Le Normand, B, Chesne-Seck, M.-L, Kocken, C.H.M, Thomas, A.W, Bentley, G.A. | Deposit date: | 2004-09-15 | Release date: | 2005-03-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal Structure of the Malaria Vaccine Candidate Apical Membrane Antigen 1 Science, 308, 2005
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4Z81
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3ZWZ
| Crystal structure of Plasmodium falciparum AMA1 in complex with a 39aa PfRON2 peptide | Descriptor: | APICAL MEMBRANE ANTIGEN 1, AMA1, GLYCEROL, ... | Authors: | Vulliez-Le Normand, B, Tonkin, M.L, Lamarque, M.H, Langer, S, Hoos, S, Roques, M, Saul, F.A, Faber, B.W, Bentley, G.A, Boulanger, M.J, Lebrun, M. | Deposit date: | 2011-08-03 | Release date: | 2012-07-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Functional Insight Into the Malaria Parasite Moving Junction Complex Plos Pathog., 8, 2012
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4Z0D
| Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038Trp] peptide | Descriptor: | Apical membrane antigen 1, Rhoptry neck protein 2 | Authors: | Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J. | Deposit date: | 2015-03-26 | Release date: | 2016-08-03 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction. J.Mol.Biol., 428, 2016
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8GIF
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6N7Q
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3SRJ
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