4Z0D

Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038Trp] peptide

Summary for 4Z0D

Entry DOI	10.2210/pdb4z0d/pdb
Related	4Z09 4Z0E 4Z0F
Descriptor	Apical membrane antigen 1, Rhoptry neck protein 2 (3 entities in total)
Functional Keywords	cell invasion, inhibitor, ama1, malaria
Biological source	Plasmodium falciparum Vietnam Oak-Knoll (FVO) More
Total number of polymer chains	2
Total formula weight	39885.64
Authors	Wang, G.,McGowan, S.,Norton, R.S.,Scanlon, M.J. (deposition date: 2015-03-26, release date: 2016-08-03, Last modification date: 2020-01-08)
Primary citation	Wang, G.,Drinkwater, N.,Drew, D.R.,MacRaild, C.A.,Chalmers, D.K.,Mohanty, B.,Lim, S.S.,Anders, R.F.,Beeson, J.G.,Thompson, P.E.,McGowan, S.,Simpson, J.S.,Norton, R.S.,Scanlon, M.J. Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction. J.Mol.Biol., 428:3986-3998, 2016 Cited by PubMed: 27422009 DOI: 10.1016/j.jmb.2016.07.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation