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4Z0E

Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038TRN] peptide

Summary for 4Z0E
Entry DOI10.2210/pdb4z0e/pdb
Related4Z09 4Z0D 4Z0F
DescriptorApical membrane antigen 1, Rhoptry neck protein 2 (3 entities in total)
Functional Keywordscell invasion, inhibitor, ama1, malaria
Biological sourcePlasmodium falciparum Vietnam Oak-Knoll (FVO)
More
Total number of polymer chains2
Total formula weight39886.62
Authors
Wang, G.,McGowan, S.,Norton, R.S.,Scanlon, M.J. (deposition date: 2015-03-26, release date: 2016-08-03, Last modification date: 2023-09-27)
Primary citationWang, G.,Drinkwater, N.,Drew, D.R.,MacRaild, C.A.,Chalmers, D.K.,Mohanty, B.,Lim, S.S.,Anders, R.F.,Beeson, J.G.,Thompson, P.E.,McGowan, S.,Simpson, J.S.,Norton, R.S.,Scanlon, M.J.
Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428:3986-3998, 2016
Cited by
PubMed: 27422009
DOI: 10.1016/j.jmb.2016.07.001
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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