Crystal structure of engineered TgAMA1 lacking the DII loop

Summary for 4YIV

DescriptorApical membrane antigen AMA1, 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... (7 entities in total)
Functional Keywordsapicomplexa, invasion, moving junction, parasite, protein engineering, pan domain, immune system
Biological sourceToxoplasma gondii ME49
Total number of polymer chains1
Total molecular weight46942.22
Parker, M.L.,Boulanger, M.J. (deposition date: 2015-03-02, release date: 2015-05-20, Last modification date: 2020-07-29)
Primary citation
Parker, M.L.,Boulanger, M.J.
An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.
Plos One, 10:e0126206-e0126206, 2015
PubMed: 25955165 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0126206
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.203300 9.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28