Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7RTS
DownloadVisualize
BU of 7rts by Molmil
Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 without the AE interface
Descriptor: Disease resistance protein RUN1, SULFATE ION
Authors:Burdett, H, Kobe, B.
Deposit date:2021-08-15
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Self-association configures the NAD + -binding site of plant NLR TIR domains
Biorxiv, 2021
6O0W
DownloadVisualize
BU of 6o0w by Molmil
Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 in complex with NADP+ and Bis-Tris
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-2'-5'-DIPHOSPHATE, TIR-NB-LRR type resistance protein RUN1
Authors:Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
Deposit date:2019-02-17
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
7YLG
DownloadVisualize
BU of 7ylg by Molmil
Crystal structure of the chicken Toll-like receptor 15 TIR domain (glutathione adduct)
Descriptor: GLUTATHIONE, Toll-like receptor 2
Authors:Ko, K.Y, Song, W.S, Yoon, S.I.
Deposit date:2022-07-26
Release date:2023-05-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of the Toll-like receptor 15 TIR domain.
Iucrj, 10, 2023
7FCJ
DownloadVisualize
BU of 7fcj by Molmil
Zebrafish SIGIRR TIR domain mutant - C299S
Descriptor: SIGIRR protein
Authors:Wang, X, Zhou, J.
Deposit date:2021-07-15
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling
Iscience, 25, 2022
7FCH
DownloadVisualize
BU of 7fch by Molmil
IL-18Rbeta TIR domain
Descriptor: Interleukin-18 receptor accessory protein
Authors:Wang, X, Zhou, J.
Deposit date:2021-07-14
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.883 Å)
Cite:Structural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling
Iscience, 25, 2022
7RX1
DownloadVisualize
BU of 7rx1 by Molmil
Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1
Descriptor: Disease resistance protein RUN1, SULFATE ION
Authors:Burdett, H, Kobe, B.
Deposit date:2021-08-21
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Self-association configures the NAD + -binding site of plant NLR TIR domains
Biorxiv, 2021
7NUW
DownloadVisualize
BU of 7nuw by Molmil
Crystal structure of the TIR domain of human TLR1 (crystallised with Zn2+ ions)
Descriptor: Toll-like receptor 1
Authors:Vakhrameev, D.D, Luginina, A.P, Shevtsov, M.B, Lushpa, V.A, Mineev, K.S, Borshchevskiy, V.I.
Deposit date:2021-03-15
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions.
Commun Biol, 4, 2021
7YLF
DownloadVisualize
BU of 7ylf by Molmil
Crystal structure of the chicken Toll-like receptor 15 TIR domain (2-mercaptoethanol adduct)
Descriptor: GLYCEROL, SULFATE ION, Toll-like receptor 15
Authors:Ko, K.Y, Song, W.S, Yoon, S.I.
Deposit date:2022-07-26
Release date:2023-05-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of the Toll-like receptor 15 TIR domain.
Iucrj, 10, 2023
3JRN
DownloadVisualize
BU of 3jrn by Molmil
Crystal structure of TIR domain from Arabidopsis Thaliana
Descriptor: ARSENIC, AT1G72930 protein
Authors:Chan, S.L, Mukasa, T, Santelli, E, Low, L.Y, Pascual, J.
Deposit date:2009-09-08
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of a TIR domain from Arabidopsis thaliana reveals a conserved helical region unique to plants.
Protein Sci., 19, 2009
4C6R
DownloadVisualize
BU of 4c6r by Molmil
Crystal structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPS4
Descriptor: DISEASE RESISTANCE PROTEIN RPS4
Authors:Williams, S.J, Sohn, K.H, Wan, L, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B.
Deposit date:2013-09-19
Release date:2014-05-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor.
Science, 344, 2014
7FCC
DownloadVisualize
BU of 7fcc by Molmil
IL-1RAcPb TIR domain
Descriptor: Isoform 4 of Interleukin-1 receptor accessory protein
Authors:Wang, X, Zhou, J.
Deposit date:2021-07-14
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.144 Å)
Cite:Structural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling
Iscience, 25, 2022
2J67
DownloadVisualize
BU of 2j67 by Molmil
The TIR domain of human Toll-Like Receptor 10 (TLR10)
Descriptor: TOLL LIKE RECEPTOR 10
Authors:Stenmark, P, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kotenyova, T, Magnusdottir, A, Nilsson, M.E, Nilsson-Ehle, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Welin, M, Nordlund, P.
Deposit date:2006-09-26
Release date:2006-09-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of the Human Toll-Like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer.
J.Biol.Chem., 283, 2008
5TEC
DownloadVisualize
BU of 5tec by Molmil
Crystal structure of the TIR domain from the Arabidopsis thaliana NLR protein SNC1
Descriptor: Protein SUPPRESSOR OF npr1-1, CONSTITUTIVE 1
Authors:Zhang, X, Bentham, A, Ve, T, Williams, S.J, Kobe, B.
Deposit date:2016-09-20
Release date:2017-02-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Multiple functional self-association interfaces in plant TIR domains.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4OM7
DownloadVisualize
BU of 4om7 by Molmil
Crystal structure of TIR domain of TLR6
Descriptor: Toll-like receptor 6
Authors:Park, H.H, Jang, T.H.
Deposit date:2014-01-26
Release date:2014-08-06
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Crystal Structure of TIR Domain of TLR6 Reveals Novel Dimeric Interface of TIR-TIR Interaction for Toll-Like Receptor Signaling Pathway.
J.Mol.Biol., 426, 2014
7WV3
DownloadVisualize
BU of 7wv3 by Molmil
Toll-like receptor3 linear cluster
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (80-MER), ...
Authors:Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O.
Deposit date:2022-02-09
Release date:2022-11-16
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
3OZI
DownloadVisualize
BU of 3ozi by Molmil
Crystal structure of the TIR domain from the flax disease resistance protein L6
Descriptor: COBALT (II) ION, L6tr
Authors:Ve, T, Bernoux, M, Williams, S, Valkov, E, Warren, C, Hatters, D, Ellis, J.G, Dodds, P.N, Kobe, B.
Deposit date:2010-09-25
Release date:2011-04-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation.
Cell Host Microbe, 9, 2011
5KU7
DownloadVisualize
BU of 5ku7 by Molmil
Crystal structure of the TIR domain from the Muscadinia rotundifolia disease resistance protein RPV1
Descriptor: MALONIC ACID, TIR-NB-LRR type resistance protein RPV1
Authors:Williams, S.J, Ericsson, D.J, Kobe, B.
Deposit date:2016-07-12
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and Function of the TIR Domain from the Grape NLR Protein RPV1.
Front Plant Sci, 7, 2016
7SZL
DownloadVisualize
BU of 7szl by Molmil
Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1R10 (IL-1RAPL2)
Descriptor: X-linked interleukin-1 receptor accessory protein-like 2
Authors:Nimma, S, Gu, W, Manik, M.K, Ve, T, Nanson, J.D, Kobe, B.
Deposit date:2021-11-28
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Toll/interleukin-1 receptor (TIR) domain of IL-1R10 provides structural insights into TIR domain signalling.
Febs Lett., 596, 2022
1T3G
DownloadVisualize
BU of 1t3g by Molmil
Crystal structure of the Toll/interleukin-1 receptor (TIR) domain of human IL-1RAPL
Descriptor: X-linked interleukin-1 receptor accessory protein-like 1
Authors:Khan, J.A, Tong, L.
Deposit date:2004-04-26
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL
J.Biol.Chem., 279, 2004
7S2Z
DownloadVisualize
BU of 7s2z by Molmil
Crystal structure of the E100A mutant TIR domain from the grapevine disease resistance protein RUN1 bound to NAD
Descriptor: Disease resistance protein RUN1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
Authors:Burdett, H, Kobe, B.
Deposit date:2021-09-04
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Self-association configures the NAD + -binding site of plant NLR TIR domains
Biorxiv, 2021
7NUX
DownloadVisualize
BU of 7nux by Molmil
Crystal structure of the TIR domain of human TLR1 (crystallised without ZN2+ ions)
Descriptor: Toll-like receptor 1
Authors:Vakhrameev, D.D, Luginina, A.P, Shevtsov, M.B, Lushpa, V.A, Mineev, K.S, Borshchevskiy, V.I.
Deposit date:2021-03-15
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions.
Commun Biol, 4, 2021
7XOZ
DownloadVisualize
BU of 7xoz by Molmil
Crystal structure of RPPT-TIR
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
Authors:Song, W, Jia, A, Huang, S, Chai, J.
Deposit date:2022-05-02
Release date:2023-11-08
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity.
Science, 377, 2022
5H3C
DownloadVisualize
BU of 5h3c by Molmil
Crystal structure of Arabidopsis SNC1 TIR domain
Descriptor: Protein SUPPRESSOR OF npr1-1, CONSTITUTIVE 1
Authors:Hyun, K.G, Yoon, J.M, Song, J.J.
Deposit date:2016-10-22
Release date:2016-12-07
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Crystal structure of Arabidopsis thaliana SNC1 TIR domain
Biochem.Biophys.Res.Commun., 481, 2016
4C6T
DownloadVisualize
BU of 4c6t by Molmil
Crystal structure of the RPS4 and RRS1 TIR domain heterodimer
Descriptor: DISEASE RESISTANCE PROTEIN RPS4, MALONIC ACID, PROBABLE WRKY TRANSCRIPTION FACTOR 52
Authors:Williams, S.J, Sohn, K.H, Wan, L, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B.
Deposit date:2013-09-19
Release date:2014-05-28
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor.
Science, 344, 2014
5TEB
DownloadVisualize
BU of 5teb by Molmil
Crystal Structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPP1
Descriptor: Recognition of Peronospora parasitica 1
Authors:Bentham, A.R, Zhang, X, Croll, T, Williams, S, Kobe, B.
Deposit date:2016-09-20
Release date:2017-02-01
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.796 Å)
Cite:Multiple functional self-association interfaces in plant TIR domains.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

 

12>

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon