4Y60
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STRUCTURE OF SOX18-HMG/PROX1-DNA
Descriptor:Transcription factor SOX-18, DNA (5'-D(*CP*AP*CP*TP*AP*GP*CP*AP*TP*TP*GP*TP*CP*TP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*AP*GP*AP*CP*AP*AP*TP*GP*CP*TP*AP*GP*T)-3')
Authors:Narasimhan, K., Prokoph, N., Kolatkar, P., Robinson, H., Jauch, R.
Deposit date:2015-02-12
Release date:2016-03-02
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.
Nucleic Acids Res., 44, 2016
5JH0
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CRYSTAL STRUCTURE OF THE MITOCHONDRIAL DNA PACKAGING PROTEIN ABF2P IN COMPLEX WITH DNA AT 2.18 ANGSTROM RESOLUTION
Descriptor:ARS-binding factor 2, mitochondrial, DNA (5'-D(*AP*AP*TP*AP*AP*TP*AP*AP*AP*TP*TP*AP*TP*AP*TP*AP*AP*TP*AP*TP*AP*A)-3'), ...
Authors:Chakraborty, A., Lyonnais, S., Sola, M.
Deposit date:2016-04-20
Release date:2017-02-08
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:DNA structure directs positioning of the mitochondrial genome packaging protein Abf2p.
Nucleic Acids Res., 45, 2017
1QRV
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CRYSTAL STRUCTURE OF THE COMPLEX OF HMG-D AND DNA
Descriptor:DNA (5'-D(*GP*CP*GP*AP*TP*AP*TP*CP*GP*C)-3'), HIGH MOBILITY GROUP PROTEIN D, SODIUM ION
Authors:Murphy IV, F.V., Sweet, R.M., Churchill, M.E.A.
Deposit date:1999-06-15
Release date:1999-12-18
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of a chromosomal high mobility group protein-DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition.
EMBO J., 18, 1999
4A3N
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CRYSTAL STRUCTURE OF HMG-BOX OF HUMAN SOX17
Descriptor:TRANSCRIPTION FACTOR SOX-17, ZINC ION
Authors:Gao, N., Gao, H., Qian, H., Si, S., Xie, Y.
Deposit date:2011-10-01
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Human Transcription Factor Sry-Related Box 17 Binding to DNA.
Protein Pept.Lett., 20, 2013
3U2B
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STRUCTURE OF THE SOX4 HMG DOMAIN BOUND TO DNA
Descriptor:DNA (5'-D(*GP*TP*CP*TP*CP*TP*AP*TP*TP*GP*TP*CP*CP*TP*GP*G)-3'), DNA (5'-D(*CP*CP*AP*GP*GP*AP*CP*AP*AP*TP*AP*GP*AP*GP*AP*C)-3'), Transcription factor SOX-4
Authors:Jauch, R., Ng, C.K.L., Kolatkar, P.R.
Deposit date:2011-10-03
Release date:2011-12-28
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism for positional interdependence in DNA recognition
Biochem.J., 443, 2012
3TQ6
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL TRANSCRIPTION FACTOR A, TFAM OR MTTFA, BOUND TO THE LIGHT STRAND PROMOTER LSP
Descriptor:Transcription factor A, mitochondrial, DNA (5'-D(*TP*AP*AP*CP*AP*GP*TP*CP*AP*CP*CP*CP*CP*CP*CP*AP*AP*CP*(BRU)P*AP*AP*C)-3'), ...
Authors:Rubio-Cosials, A., Sydow, J.F., Jimenez-Menendez, N., Fernandez-Millan, P., Montoya, J., Jacobs, H.T., Coll, M., Bernado, P., Sola, M.
Deposit date:2011-09-09
Release date:2011-11-02
Last modified:2017-01-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter.
Nat.Struct.Mol.Biol., 18, 2011
3TMM
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TFAM IMPOSES A U-TURN ON MITOCHONDRIAL DNA
Descriptor:Transcription factor A, mitochondrial, DNA (28-MER)
Authors:Ngo, H.B., Kaiser, J.T., Chan, D.C.
Deposit date:2011-08-31
Release date:2011-11-09
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.5001 Å)
Cite:The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA.
Nat.Struct.Mol.Biol., 18, 2011
1GT0
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CRYSTAL STRUCTURE OF A POU/HMG/DNA TERNARY COMPLEX
Descriptor:5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*TP*TP* GP*GP*AP* TP*GP*CP*TP*AP*AP*TP*GP*GP*GP*A)-3', 5'-D(*AP*TP*CP*CP*CP*AP*TP*TP*AP*GP* CP*AP*TP*CP*CP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1, ...
Authors:Remenyi, A., Wilmanns, M.
Deposit date:2002-01-09
Release date:2003-01-30
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of a POU/Hmg/DNA Ternary Complex Suggests Differential Assembly of Oct4 and Sox2 on Two Enhancers
Genes Dev., 17, 2003
5JGH
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CRYSTAL STRUCTURE OF THE MITOCHONDRIAL DNA PACKAGING PROTEIN ABF2P IN COMPLEX WITH DNA AT 2.6 ANGSTROM RESOLUTION
Descriptor:ARS-binding factor 2, mitochondrial, DNA (5'-D(*TP*TP*TP*AP*TP*TP*AP*TP*TP*TP*TP*AP*TP*AP*TP*TP*AP*TP*AP*TP*AP*A)-3'), ...
Authors:Chakraborty, A., Lyonnais, S., Sola, M.
Deposit date:2016-04-20
Release date:2017-02-08
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:DNA structure directs positioning of the mitochondrial genome packaging protein Abf2p.
Nucleic Acids Res., 45, 2017
4S2Q
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CRYSTAL STRUCTURE OF HMG DOMAIN OF THE CHONDROGENESIS MASTER REGULATOR, SOX9 IN COMPLEX WITH CHIP-SEQ IDENTIFIED DNA ELEMENT
Descriptor:DNA (5'-D(P*AP*GP*GP*CP*TP*TP*TP*GP*TP*TP*CP*TP*CP*CP*TP*G)-3'), DNA (5'-D(P*AP*GP*GP*AP*GP*AP*AP*CP*AP*AP*AP*GP*CP*CP*TP*G)-3'), Transcription factor SOX-9
Authors:Vivekanandan, S., Moovarkumudalvan, B., Lescar, J., Kolatkar, P.R.
Deposit date:2015-01-21
Release date:2016-02-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of HMG domain of the chondrogenesis master regulator, Sox9 in complex with ChIP-Seq identified DNA element
To be Published
3F27
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STRUCTURE OF SOX17 BOUND TO DNA
Descriptor:DNA (5'-D(*DGP*DTP*DCP*DTP*DCP*DTP*DAP*DTP*DTP*DGP*DTP*DCP*DCP*DTP*DGP*DG)-3'), DNA (5'-D(*DCP*DCP*DAP*DGP*DGP*DAP*DCP*DAP*DAP*DTP*DAP*DGP*DAP*DGP*DAP*DC)-3'), Transcription factor SOX-17
Authors:Palasingam, P., Jauch, R., Ng, C.K.L., Kolatkar, P.R.
Deposit date:2008-10-29
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The Structure of Sox17 Bound to DNA Reveals a Conserved Bending Topology but Selective Protein Interaction Platforms
J.Mol.Biol., 388, 2009
5ZE0
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HAIRPIN FORMING COMPLEX, RAG1/2-NICKED(WITH DIDEOXY) 12RSS/23RSS COMPLEX IN MG2+
Descriptor:mouse RAG1, mouse RAG2, HMGB1 A-B box, ...
Authors:Kim, M.S., Chuenchor, W., Chen, X., Gellert, M., Yang, W.
Deposit date:2018-02-25
Release date:2018-04-25
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
4EUW
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CRYSTAL STRUCTURE OF A HMG DOMAIN OF TRANSCRIPTION FACTOR SOX-9 BOUND TO DNA (SOX-9/DNA) FROM HOMO SAPIENS AT 2.77 A RESOLUTION
Descriptor:Transcription factor SOX-9, DNA (5'-D(*CP*TP*CP*TP*TP*TP*GP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*CP*AP*AP*AP*GP*AP*G)-3')
Authors:Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL)
Deposit date:2012-04-25
Release date:2012-06-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Crystal structure of a HMG domain of transcription factor SOX-9 bound to DNA (SOX-9/DNA) from Homo sapiens at 2.77 A resolution
To be published
5ZDZ
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HAIRPIN FORMING COMPLEX, RAG1/2-NICKED 12RSS/23RSS COMPLEX IN CA2+
Descriptor:mouse RAG1, mouse RAG2, HMGB1 A-B box, ...
Authors:Kim, M.S., Chuenchor, W., Chen, X., Gellert, M., Yang, W.
Deposit date:2018-02-25
Release date:2018-04-25
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
4NNU
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DISTINCT STRUCTURAL FEATURES OF TFAM DRIVE MITOCHONDRIAL DNA PACKAGING VERSUS TRANSCRIPTIONAL ACTIVATION
Descriptor:Transcription factor A, mitochondrial, DNA1, ...
Authors:Ngo, H.B., Lovely, G.A., Phillips, R., Chan, D.C.
Deposit date:2013-11-19
Release date:2014-01-22
Last modified:2017-01-11
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
Nat Commun, 5, 2014
3NM9
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HMGD(M13A)-DNA COMPLEX
Descriptor:High mobility group protein D, DNA 5'-D(*G*GP*CP*GP*AP*TP*AP*TP*CP*GP*C)-3'
Authors:Churchill, M.E.A., Klass, J., Zoetewey, D.L.
Deposit date:2010-06-22
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural analysis of HMGD-DNA complexes reveals influence of intercalation on sequence selectivity and DNA bending.
J.Mol.Biol., 403, 2010
4NOD
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DISTINCT STRUCTURAL FEATURES OF TFAM DRIVE MITOCHONDRIAL DNA PACKAGING VERSUS TRANSCRIPTIONAL ACTIVATION
Descriptor:Transcription factor A, mitochondrial, 5'-D(*TP*TP*GP*GP*GP*GP*TP*AP*TP*GP*GP*GP*GP*CP*TP*TP*GP*GP*(BRU)P*TP*GP*G)-3', ...
Authors:Ngo, H.B., Lovely, G.A., Phillips, R., Chan, D.C.
Deposit date:2013-11-19
Release date:2014-01-22
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.897 Å)
Cite:Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
Nat Commun, 5, 2014
5ZE1
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HAIRPIN FORMING COMPLEX, RAG1/2-NICKED 12RSS/23RSS COMPLEX IN 2MM MN2+ FOR 10 MIN AT 4'C
Descriptor:mouse RAG1, mouse RAG2, HMGB1 A-B box, ...
Authors:Kim, M.S., Chuenchor, W., Chen, X., Gellert, M., Yang, W.
Deposit date:2018-02-25
Release date:2018-04-25
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
6CIK
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PRE-REACTION COMPLEX, RAG1(E962Q)/2-INTACT/NICKED 12/23RSS COMPLEX IN MN2+
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, High mobility group protein B1, ...
Authors:Chuenchor, W., Chen, X., Kim, M.S., Gellert, M., Yang, W.
Deposit date:2018-02-24
Release date:2018-04-25
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
5ZE2
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HAIRPIN COMPLEX, RAG1/2-HAIRPIN 12RSS/23RSS COMPLEX IN 5MM MN2+ FOR 2 MIN AT 4'C
Descriptor:mouse RAG1, mouse RAG2, HMGB1 A-B box, ...
Authors:Kim, M.S., Chuenchor, W., Chen, X., Gellert, M., Yang, W.
Deposit date:2018-02-25
Release date:2018-04-25
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Cracking the DNA Code for V(D)J Recombination
Mol. Cell, 70, 2018
6CIM
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PRE-REACTION COMPLEX, RAG1(E962Q)/2-NICKED/INTACT 12/23RSS COMPLEX IN MN2+
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, High mobility group protein B1, ...
Authors:Chuenchor, W., Chen, X., Kim, M.S., Gellert, M., Yang, W.
Deposit date:2018-02-24
Release date:2018-04-25
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CIJ
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CRYO-EM STRUCTURE OF MOUSE RAG1/2 HFC COMPLEX CONTAINING PARTIAL HMGB1 LINKER(3.9 A)
Descriptor:V(D)J recombination-activating protein 1, DNA (46-MER), DNA (5'-D(*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), ...
Authors:Chen, X., Kim, M., Chuenchor, W., Cui, Y., Zhang, X., Zhou, Z.H., Gellert, M., Yang, W.
Deposit date:2018-02-24
Release date:2018-04-25
Last modified:2018-05-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6CIL
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PRE-REACTION COMPLEX, RAG1(E962Q)/2-INTACT/INTACT 12/23RSS COMPLEX IN MN2+
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, High mobility group protein B1, ...
Authors:Chuenchor, W., Chen, X., Kim, M.S., Gellert, M., Yang, W.
Deposit date:2018-02-24
Release date:2018-04-25
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (4.15 Å)
Cite:Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
6ERQ
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STRUCTURE OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION INITIATION COMPLEX AT THE HSP PROMOTER
Descriptor:Transcription factor A, mitochondrial, Non-Template DNA, ...
Authors:Hillen, H.S., Morozov, Y.I., Sarfallah, A., Temiakov, D., Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
6ERP
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STRUCTURE OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION INITIATION COMPLEX AT THE LSP PROMOTER
Descriptor:Transcription factor A, mitochondrial, Non-Template DNA, ...
Authors:Hillen, H.S., Morozov, Y.I., Sarfallah, A., Temiakov, D., Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (4.502 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
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