3TQ6
Crystal structure of human mitochondrial transcription factor A, TFAM or mtTFA, bound to the light strand promoter LSP
Summary for 3TQ6
Entry DOI | 10.2210/pdb3tq6/pdb |
Descriptor | Transcription factor A, mitochondrial, DNA (5'-D(*TP*AP*AP*CP*AP*GP*TP*CP*AP*CP*CP*CP*CP*CP*CP*AP*AP*CP*(BRU)P*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*AP*GP*TP*TP*GP*GP*GP*GP*GP*GP*TP*GP*AP*CP*TP*GP*TP*TP*A)-3'), ... (7 entities in total) |
Functional Keywords | transcription, transcription regulation, mitochondrion, dna-binding, hmgb-ubf_hmg-box, minor groove, tandem hmg boxes, transcription-dna complex, mitochondrial nucleoid, light-strand mitochondrial promoter, lsp, transcription/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Mitochondrion: Q00059 |
Total number of polymer chains | 6 |
Total formula weight | 78993.82 |
Authors | Rubio-Cosials, A.,Sydow, J.F.,Jimenez-Menendez, N.,Fernandez-Millan, P.,Montoya, J.,Jacobs, H.T.,Coll, M.,Bernado, P.,Sola, M. (deposition date: 2011-09-09, release date: 2011-11-02, Last modification date: 2024-02-28) |
Primary citation | Rubio-Cosials, A.,Sidow, J.F.,Jimenez-Menendez, N.,Fernandez-Millan, P.,Montoya, J.,Jacobs, H.T.,Coll, M.,Bernado, P.,Sola, M. Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter. Nat.Struct.Mol.Biol., 18:1281-1289, 2011 Cited by PubMed: 22037172DOI: 10.1038/nsmb.2160 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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