4EUW

Crystal structure of a HMG domain of transcription factor SOX-9 bound to DNA (SOX-9/DNA) from Homo sapiens at 2.77 A resolution

Summary for 4EUW

DescriptorTranscription factor SOX-9, DNA (5'-D(*CP*TP*CP*TP*TP*TP*GP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*CP*AP*AP*AP*GP*AP*G)-3'), ... (4 entities in total)
Functional Keywordsprotein-dna complex, hmg domain, activator, dna-binding, nucleus, transcription, transcription regulation, structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-biology, partnership for stem cell biology, stemcell, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (human)
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Total number of polymer chains3
Total molecular weight20241.54
Authors
Joint Center for Structural Genomics (JCSG),Partnership for Stem Cell Biology (STEMCELL) (deposition date: 2012-04-25, release date: 2012-06-13, Last modification date: 2019-07-17)
Primary citation
Joint Center for Structural Genomics (JCSG),Partnership for Stem Cell Biology
Crystal structure of a HMG domain of transcription factor SOX-9 bound to DNA (SOX-9/DNA) from Homo sapiens at 2.77 A resolution
To be published,
Experimental method
X-RAY DIFFRACTION (2.77 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.273300 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-09-16