5DWY
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CRYSTAL STRUCTURE OF A SUBSTRATE-FREE GLUTAMATE TRANSPORTER HOMOLOGUE GLTTK
Descriptor:Proton/glutamate symporter, SDF family, TRIETHYLENE GLYCOL, ...
Authors:Guskov, A., Slotboom, D.J.
Deposit date:2015-09-23
Release date:2016-09-28
Last modified:2016-11-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk.
Nat Commun, 7, 2016
5E9S
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CRYSTAL STRUCTURE OF SUBSTRATE-BOUND GLUTAMATE TRANSPORTER HOMOLOGUE GLTTK
Descriptor:Proton/glutamate symporter, SDF family, ASPARTIC ACID, ...
Authors:Guskov, A., Slotboom, D.J.
Deposit date:2015-10-15
Release date:2016-09-28
Last modified:2016-11-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk.
Nat Commun, 7, 2016
2NWL
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CRYSTAL STRUCTURE OF GLTPH IN COMPLEX WITH L-ASP
Descriptor:glutamate symport protein, PALMITIC ACID, ASPARTIC ACID
Authors:Gouaux, E., Boudker, O., Ryan, R., Yernool, D., Shimamoto, K.
Deposit date:2006-11-15
Release date:2007-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
4KY0
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CRYSTAL STRUCTURE OF A SUBSTRATE-FREE GLUTAMATE TRANSPORTER HOMOLOGUE FROM THERMOCOCCUS KODAKARENSIS
Descriptor:Proton/glutamate symporter, SDF family, TETRAETHYLENE GLYCOL
Authors:Guskov, A., Jensen, S., Rempel, S., Hanelt, I., Slotboom, D.J.
Deposit date:2013-05-28
Release date:2013-09-11
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a substrate-free aspartate transporter.
Nat.Struct.Mol.Biol., 20, 2013
2NWW
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CRYSTAL STRUCTURE OF GLTPH IN COMPLEX WITH TBOA
Descriptor:425aa long hypothetical proton glutamate symport protein, (3S)-3-(BENZYLOXY)-L-ASPARTIC ACID
Authors:Gouaux, E., Boudker, O., Ryan, R., Yernool, D., Shimamoto, K.
Deposit date:2006-11-16
Release date:2007-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
4P19
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CLOSED, APO INWARD-FACING STATE OF THE GLUTAMATE TRANSPORTER HOMOLOGUE GLTPH
Descriptor:425aa long hypothetical proton glutamate symport protein, MERCURY (II) ION
Authors:Verdon, G., Boudker, O.
Deposit date:2014-02-25
Release date:2014-06-04
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
2NWX
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CRYSTAL STRUCTURE OF GLTPH IN COMPLEX WITH L-ASPARTATE AND SODIUM IONS
Descriptor:425aa long hypothetical proton glutamate symport protein, SODIUM ION, ASPARTIC ACID, ...
Authors:Gouaux, E., Boudker, O., Ryan, R., Yernool, D., Shimamoto, K.
Deposit date:2006-11-16
Release date:2007-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter.
Nature, 445, 2007
6BAT
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CRYSTAL STRUCTURE OF WILD-TYPE GLTPH IN COMPLEX WITH L-ASPARTATE
Descriptor:Glutamate transporter homolog, SODIUM ION, ASPARTIC ACID
Authors:Font, J., Scopelliti, A.J., Vandenberg, R.J., Boudker, O., Ryan, R.M.
Deposit date:2017-10-15
Release date:2018-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
4OYF
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CRYSTAL STRUCTURE OF GLTPH R397A IN SODIUM-BOUND STATE
Descriptor:GLUTAMATE SYMPORT PROTEIN, SODIUM ION
Authors:Boudker, O., Oh, S., Verdon, G., Serio, R.
Deposit date:2014-02-11
Release date:2014-08-13
Last modified:2015-01-07
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
1XFH
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STRUCTURE OF GLUTAMATE TRANSPORTER HOMOLOG FROM PYROCOCCUS HORIKOSHII
Descriptor:proton glutamate symport protein
Authors:Yernool, D., Boudker, O., Jin, Y., Gouaux, E.
Deposit date:2004-09-14
Release date:2004-10-26
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a glutamate transporter homologue from Pyrococcus horikoshii
Nature, 431, 2004
4P3J
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APO INWARD-FACING STATE OF THE GLUTAMATE TRANSPORTER HOMOLOGUE GLTPH IN ALKALI-FREE CONDITIONS
Descriptor:GltPh, MERCURY (II) ION
Authors:Verdon, G., Boudker, O.
Deposit date:2014-03-08
Release date:2014-06-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
5CFY
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CRYSTAL STRUCTURE OF GLTPH R397A IN COMPLEX WITH NA+ AND L-ASP
Descriptor:425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, SODIUM ION
Authors:Boudker, O., Oh, S.
Deposit date:2015-07-08
Release date:2016-04-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
3KBC
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CRYSTAL STRUCTURE OF GLTPH K55C-A364C MUTANT CROSSLINKED WITH DIVALENT MERCURY
Descriptor:425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, MERCURY (II) ION, ...
Authors:Reyes, N., Ginter, C., Boudker, O.
Deposit date:2009-10-20
Release date:2009-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Transport mechanism of a bacterial homologue of glutamate transporters.
Nature, 462, 2009
6BAV
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CRYSTAL STRUCTURE OF GLTPH R397C IN COMPLEX WITH S-BENZYL-L-CYSTEINE
Descriptor:Glutamate transporter homolog, SODIUM ION, BENZYLCYSTEINE
Authors:Font, J., Scopelliti, A.J., Vandenberg, R.J., Boudker, O., Ryan, R.M.
Deposit date:2017-10-16
Release date:2018-01-17
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
4P1A
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THALLIUM-BOUND INWARD-FACING STATE OF THE GLUTAMATE TRANSPORTER HOMOLOGUE GLTPH
Descriptor:GltPh, THALLIUM (I) ION, MERCURY (II) ION
Authors:Verdon, G., Boudker, O.
Deposit date:2014-02-25
Release date:2014-06-04
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
3V8F
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CRYSTAL STRUCTURE OF CROSSLINKED GLTPH V216C-M385C MUTANT
Descriptor:sodium-coupled L-aspartate transporter, ASPARTIC ACID, SODIUM ION, ...
Authors:Verdon, G., Boudker, O.
Deposit date:2011-12-22
Release date:2012-02-15
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of an asymmetric trimer of a bacterial glutamate transporter homolog.
Nat.Struct.Mol.Biol., 19, 2012
6BAU
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CRYSTAL STRUCTURE OF GLTPH R397C IN COMPLEX WITH L-CYSTEINE
Descriptor:Glutamate transporter homolog, SODIUM ION, CYSTEINE
Authors:Font, J., Scopelliti, A.J., Vandenberg, R.J., Boudker, O., Ryan, R.M.
Deposit date:2017-10-15
Release date:2018-01-17
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
6GCT
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CRYO-EM STRUCTURE OF THE HUMAN NEUTRAL AMINO ACID TRANSPORTER ASCT2
Descriptor:Neutral amino acid transporter B(0), GLUTAMINE
Authors:Garaeva, A.A., Oostergetel, G.T., Gati, C., Guskov, A., Paulino, C., Slotboom, D.J.
Deposit date:2018-04-19
Release date:2018-06-13
Last modified:2018-06-20
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Cryo-EM structure of the human neutral amino acid transporter ASCT2.
Nat. Struct. Mol. Biol., 25, 2018
6BMI
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CRYSTAL STRUCTURE OF GLTPH R397C IN COMPLEX WITH L-SERINE
Descriptor:Glutamate transporter homolog, SODIUM ION, SERINE
Authors:Font, J., Scopelliti, A.J., Vandenberg, R.J., Boudker, O., Ryan, R.M.
Deposit date:2017-11-14
Release date:2018-01-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5.
Nat Commun, 9, 2018
4OYE
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CRYSTAL STRUCTURE OF GLTPH R397A IN APO
Descriptor:425aa long hypothetical proton glutamate symport protein
Authors:Boudker, O., Oh, S.
Deposit date:2014-02-11
Release date:2014-09-17
Method:X-RAY DIFFRACTION (4 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
6CTF
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CRYSTAL STRUCTURE OF GLTPH FAST MUTANT - R276S/M395R
Descriptor:Glutamate transporter homolog, ASPARTIC ACID, SODIUM ION
Authors:Boudker, O., Oh, S.
Deposit date:2018-03-23
Release date:2018-10-10
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (4.05 Å)
Cite:Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh.
Elife, 7, 2018
4P6H
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TL+-BOUND INWARD-FACING STATE (BOUND CONFORMATION) OF THE GLUTAMATE TRANSPORTER HOMOLOGUE GLTPH
Descriptor:GltPh, MERCURY (II) ION, THALLIUM (I) ION
Authors:Verdon, G., Boudker, O.
Deposit date:2014-03-24
Release date:2014-06-04
Method:X-RAY DIFFRACTION (4.08 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
4X2S
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CRYSTAL STRUCTURE OF 276S/M395R-GLTPH IN INWARD-FACING CONFORMATION
Descriptor:425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, SODIUM ION
Authors:Akyuz, N., Boudker, O.
Deposit date:2014-11-26
Release date:2015-02-04
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (4.21 Å)
Cite:Transport domain unlocking sets the uptake rate of an aspartate transporter.
Nature, 518, 2015
4IZM
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CRYSTAL STRUCTURE OF GLTPH L66C-S300C MUTANT CROSSLINKED WITH DIVALENT MERCURY
Descriptor:425aa long hypothetical proton glutamate symport protein, SODIUM ION, ASPARTIC ACID, ...
Authors:Reyes, N., Boudker, O.
Deposit date:2013-01-30
Release date:2013-04-10
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Binding thermodynamics of a glutamate transporter homolog.
Nat.Struct.Mol.Biol., 20, 2013
3V8G
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CRYSTAL STRUCTURE OF AN ASYMMETRIC TRIMER OF A GLUTAMATE TRANSPORTER HOMOLOGUE (GLTPH)
Descriptor:sodium-coupled L-aspartate transporter, ASPARTIC ACID, SODIUM ION
Authors:Verdon, G., Boudker, O.
Deposit date:2011-12-22
Release date:2012-02-15
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (4.66 Å)
Cite:Crystal structure of an asymmetric trimer of a bacterial glutamate transporter homolog.
Nat.Struct.Mol.Biol., 19, 2012
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