5LLU
Structure of the thermostabilized EAAT1 cryst-II mutant in complex with L-ASP
Summary for 5LLU
Entry DOI | 10.2210/pdb5llu/pdb |
Related | 5LLM |
Descriptor | Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, SODIUM ION, ASPARTIC ACID (3 entities in total) |
Functional Keywords | excitatory amino acid transporter 1, human glutamate transporter, slc1a3, thermostabilized, transport protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Membrane; Multi-pass membrane protein: P43003 |
Total number of polymer chains | 1 |
Total formula weight | 56616.42 |
Authors | Canul-Tec, J.,Assal, R.,Legrand, P.,Reyes, N. (deposition date: 2016-07-28, release date: 2017-04-19, Last modification date: 2024-01-10) |
Primary citation | Canul-Tec, J.C.,Assal, R.,Cirri, E.,Legrand, P.,Brier, S.,Chamot-Rooke, J.,Reyes, N. Structure and allosteric inhibition of excitatory amino acid transporter 1. Nature, 544:446-451, 2017 Cited by PubMed: 28424515DOI: 10.1038/nature22064 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.32 Å) |
Structure validation
Download full validation report