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1BDH
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR)
Authors:Glasfeld, A, Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G.
Deposit date:1996-07-25
Release date:1997-04-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Positively Charged Residue Bound in the Minor Groove Does not Alter the Bending of a DNA Duplex
J.Am.Chem.Soc., 118, 1996
1BDI
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR)
Authors:Glasfeld, A, Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G.
Deposit date:1996-07-25
Release date:1997-04-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Positively Charged Residue Bound in the Minor Groove Does not Alter the Bending of a DNA Duplex
J.Am.Chem.Soc., 118, 1996
1CJG
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NMR STRUCTURE OF LAC REPRESSOR HP62-DNA COMPLEX
Descriptor: DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3'), PROTEIN (LAC REPRESSOR)
Authors:Spronk, C.A.E.M, Bonvin, A.M.J.J, Radha, P.K, Melacini, G, Boelens, R, Kaptein, R.
Deposit date:1999-04-14
Release date:2000-01-01
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The solution structure of Lac repressor headpiece 62 complexed to a symmetrical lac operator.
Structure Fold.Des., 7, 1999
1EFA
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CRYSTAL STRUCTURE OF THE LAC REPRESSOR DIMER BOUND TO OPERATOR AND THE ANTI-INDUCER ONPF
Descriptor: 2-nitrophenyl beta-D-fucopyranoside, DNA (5'-D(*GP*AP*AP*T*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), LAC REPRESSOR
Authors:Bell, C.E, Lewis, M.
Deposit date:2000-02-07
Release date:2000-03-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A closer view of the conformation of the Lac repressor bound to operator.
Nat.Struct.Biol., 7, 2000
1JFS
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX
Descriptor: 5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR
Authors:Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G.
Deposit date:2001-06-21
Release date:2002-02-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.
Biochemistry, 41, 2002
1JFT
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX
Descriptor: 5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PHOSPHATE ION, ...
Authors:Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G.
Deposit date:2001-06-21
Release date:2002-02-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.
Biochemistry, 41, 2002
1JH9
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX
Descriptor: 5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T)-3', HYPOXANTHINE, PHOSPHATE ION, ...
Authors:Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G.
Deposit date:2001-06-27
Release date:2002-02-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.
Biochemistry, 41, 2002
1JWL
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Structure of the Dimeric lac Repressor/Operator O1/ONPF Complex
Descriptor: 2-nitrophenyl beta-D-fucopyranoside, 5'-D(*AP*GP*AP*AP*T*TP*GP*TP*GP*AP*GP*CP*GP*GP*AP*TP*AP*AP*CP*AP*AP*TP*T)-3', 5'-D(*TP*AP*AP*TP*TP*GP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3', ...
Authors:Bell, C.E, Lewis, M.
Deposit date:2001-09-04
Release date:2001-10-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystallographic analysis of Lac repressor bound to natural operator O1.
J.Mol.Biol., 312, 2001
1JYE
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Structure of a Dimeric Lac Repressor with C-terminal Deletion and K84L Substitution
Descriptor: GLYCEROL, Lactose Operon Repressor
Authors:Bell, C.E, Barry, J, Matthews, K.S, Lewis, M.
Deposit date:2001-09-12
Release date:2001-10-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of a variant of lac repressor with increased thermostability and decreased affinity for operator.
J.Mol.Biol., 313, 2001
1JYF
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Structure of the Dimeric Lac Repressor with an 11-residue C-terminal Deletion.
Descriptor: GLYCEROL, Lactose Operon Repressor
Authors:Bell, C.E, Barry, J, Matthews, K.S, Lewis, M.
Deposit date:2001-09-12
Release date:2001-10-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a variant of lac repressor with increased thermostability and decreased affinity for operator.
J.Mol.Biol., 313, 2001
1L1M
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SOLUTION STRUCTURE OF A DIMER OF LAC REPRESSOR DNA-BINDING DOMAIN COMPLEXED TO ITS NATURAL OPERATOR O1
Descriptor: 5'-D(*AP*AP*AP*TP*TP*GP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*GP*AP*TP*AP*AP*CP*AP*AP*TP*TP*T)-3', Lactose operon repressor
Authors:Kalodimos, C.G, Bonvin, A.M.J.J, Salinas, R.K, Wechselberger, R, Boelens, R, Kaptein, R.
Deposit date:2002-02-19
Release date:2002-06-26
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Plasticity in protein-DNA recognition: lac repressor interacts with its natural operator 01 through alternative conformations of its DNA-binding domain.
EMBO J., 21, 2002
1LBG
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LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY
Descriptor: DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), PROTEIN (LACTOSE OPERON REPRESSOR)
Authors:Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P.
Deposit date:1996-01-03
Release date:1996-02-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
1LBH
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INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG
Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG
Authors:Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P.
Deposit date:1996-02-17
Release date:1996-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
1LBI
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LAC REPRESSOR
Descriptor: LAC REPRESSOR
Authors:Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P.
Deposit date:1996-02-17
Release date:1996-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
1LCC
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BU of 1lcc by Molmil
STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS
Descriptor: DNA (5'-D(*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), Lac Repressor, ...
Authors:Chuprina, V.P, Rullmann, J.A.C, Lamerichs, R.M.J.N, Van Boom, J.H, Boelens, R, Kaptein, R.
Deposit date:1993-03-25
Release date:1994-01-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics.
J.Mol.Biol., 234, 1993
1LCD
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BU of 1lcd by Molmil
STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS
Descriptor: DNA (5'-D(*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), Lac Repressor, ...
Authors:Chuprina, V.P, Rullmann, J.A.C, Lamerichs, R.M.J.N, Van Boom, J.H, Boelens, R, Kaptein, R.
Deposit date:1993-03-25
Release date:1994-01-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics.
J.Mol.Biol., 234, 1993
1LQC
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LAC REPRESSOR HEADPIECE (RESIDUES 1-56), NMR, 32 STRUCTURES
Descriptor: LAC REPRESSOR
Authors:Slijper, M, Bonvin, A.M.J.J, Boelens, R, Kaptein, R.
Deposit date:1996-08-13
Release date:1997-02-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Refined structure of lac repressor headpiece (1-56) determined by relaxation matrix calculations from 2D and 3D NOE data: change of tertiary structure upon binding to the lac operator.
J.Mol.Biol., 259, 1996
1OSL
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BU of 1osl by Molmil
Solution structure of a dimeric lactose DNA-binding domain complexed to a nonspecific DNA sequence
Descriptor: 5'-D(*CP*GP*AP*TP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*AP*TP*CP*G)-3', Lactose operon repressor
Authors:Kalodimos, C.G, Bonvin, A.M.J.J, Boelens, R, Kaptein, R.
Deposit date:2003-03-20
Release date:2004-05-04
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.
Science, 305, 2004
1PNR
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BU of 1pnr by Molmil
PURINE REPRESSOR-HYPOXANTHINE-PURF-OPERATOR COMPLEX
Descriptor: DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR)
Authors:Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G.
Deposit date:1995-03-29
Release date:1995-11-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
1PRU
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PURINE REPRESSOR DNA-BINDING DOMAIN DNA BINDING
Descriptor: PURINE REPRESSOR
Authors:Nagadoi, A, Morikawa, S, Nakamura, H, Enari, M, Kobayashi, K, Yamamoto, H, Sampei, G, Mizobuchi, K, Schumacher, M.A, Brennan, R.G, Nishimura, Y.
Deposit date:1995-05-08
Release date:1996-03-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain.
Structure, 3, 1995
1PRV
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PURINE REPRESSOR DNA-BINDING DOMAIN DNA BINDING
Descriptor: PURINE REPRESSOR
Authors:Nagadoi, A, Morikawa, S, Nakamura, H, Enari, M, Kobayashi, K, Yamamoto, H, Sampei, G, Mizobuchi, K, Schumacher, M.A, Brennan, R.G, Nishimura, Y.
Deposit date:1995-05-08
Release date:1996-03-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain.
Structure, 3, 1995
1QP0
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PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*CP*CP*GP*GP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
Authors:Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
Deposit date:1999-06-01
Release date:1999-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QP4
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PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*TP*CP*GP*AP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
Authors:Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
Deposit date:1999-06-01
Release date:1999-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QP7
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*CP*CP*GP*GP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
Authors:Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
Deposit date:1999-06-01
Release date:1999-06-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QPZ
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PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
Descriptor: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
Authors:Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
Deposit date:1999-06-01
Release date:1999-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999

 

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