Solution structure of a dimeric lactose DNA-binding domain complexed to a nonspecific DNA sequence

Summary for 1OSL

Descriptor5'-D(*CP*GP*AP*TP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*AP*TP*CP*G)-3', Lactose operon repressor (2 entities in total)
Functional Keywordsprotein-dna complex, lac repressor, nonspecific interaction, transcription-dna complex, transcription/dna
Biological sourceEscherichia coli
Total number of polymer chains4
Total molecular weight24674.72
Kalodimos, C.G.,Bonvin, A.M.J.J.,Boelens, R.,Kaptein, R. (deposition date: 2003-03-20, release date: 2004-05-04, Last modification date: 2011-07-13)
Primary citation
Kalodimos, C.G.,Biris, N.,Bonvin, A.M.,Levandoski, M.M.,Guennuegues, M.,Boelens, R.,Kaptein, R.
Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.
Science, 305:386-389, 2004
PubMed: 15256668 (PDB entries with the same primary citation)
DOI: 10.1126/science.1097064
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers180.1%17.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures