9EZL
 
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8YIF
 | | Crystal structure of GH13_30 alpha-glucosidase CmmB in complex with acarviosin | | Descriptor: | Acarviosin, Alpha-glucosidase | | Authors: | Saburi, W, Tagami, T, Yu, J, Ose, T, Yao, M, Mori, H. | | Deposit date: | 2024-02-29 | | Release date: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Molecular mechanism for the substrate specificity of Arthrobacter globiformis M6 alpha-glucosidase CmmB, belonging to glycoside hydrolase family 13 subfamily 30
Food Biosci, 61, 2024
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8YIE
 | | Crystal structure of GH13_30 alpha-glucosidase CmmB in complex with acarbose | | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-glucosidase | | Authors: | Saburi, W, Tagami, T, Yu, J, Ose, T, Yao, M, Mori, H. | | Deposit date: | 2024-02-29 | | Release date: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Molecular mechanism for the substrate specificity of Arthrobacter globiformis M6 alpha-glucosidase CmmB, belonging to glycoside hydrolase family 13 subfamily 30
Food Biosci, 61, 2024
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8XXA
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8XX9
 | | Rhodothermus marinus alpha-amylase RmGH13_47A CBM48-A-B-C domains | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Tonozuka, T. | | Deposit date: | 2024-01-18 | | Release date: | 2024-02-07 | | Last modified: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural basis for the recognition of alpha-1,6-branched alpha-glucan by GH13_47 alpha-amylase from Rhodothermus marinus.
Proteins, 92, 2024
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8XPU
 | | Overall structure of the LAT1-4F2hc bound with JPH203 | | Descriptor: | (2~{S})-2-azanyl-3-[4-[(5-azanyl-2-phenyl-1,3-benzoxazol-7-yl)methoxy]-3,5-bis(chloranyl)phenyl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 5 of Amino acid transporter heavy chain SLC3A2, ... | | Authors: | Hu, Z, Yan, R. | | Deposit date: | 2024-01-04 | | Release date: | 2024-07-17 | | Last modified: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis for the inhibition mechanism of LAT1-4F2hc complex by JPH203.
Cell Discov, 10, 2024
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8UZH
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8UQV
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8WNS
 | | Cryo EM map of SLC7A10 in the apo state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1 | | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | Deposit date: | 2023-10-06 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
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8WNY
 | | Cryo EM map of SLC7A10-SLC3A2 complex in the D-serine bound state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1, ... | | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | Deposit date: | 2023-10-06 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
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8WNT
 | | Cryo EM map of SLC7A10 with L-Alanine substrate | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALANINE, ... | | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | Deposit date: | 2023-10-06 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
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8QEY
 | | Structure of human Asc1/CD98hc heteromeric amino acid transporter | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | | Authors: | Martinez-Molledo, M, Rullo-Tubau, J, Errasti-Murugarren, E, Palacin, M, Llorca, O. | | Deposit date: | 2023-09-01 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter.
Nat Commun, 15, 2024
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8JNX
 | | alkaline amylase Amy703 with truncated of N-terminus domain | | Descriptor: | Alpha-amylase, CALCIUM ION | | Authors: | Xiang, L, Zhang, G, Zhou, J. | | Deposit date: | 2023-06-06 | | Release date: | 2023-12-13 | | Last modified: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (3.20279884 Å) | | Cite: | N-terminal domain truncation yielded a unique dimer of polysaccharide hydrolase with enhanced enzymatic activity, stability and calcium ion independence.
Int.J.Biol.Macromol., 266, 2024
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8JJM
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8J8L
 | | Overall structure of the LAT1-4F2hc bound with L-dopa | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-DIHYDROXYPHENYLALANINE, 4F2 cell-surface antigen heavy chain, ... | | Authors: | Yan, R.H, Li, Y.N, Shi, T.H. | | Deposit date: | 2023-05-02 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | Overall structure of the LAT1-4F2hc bound with L-dopa
To Be Published
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8J8M
 | | Overall structure of the LAT1-4F2hc bound with tryptophan | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, Large neutral amino acids transporter small subunit 1, ... | | Authors: | Yan, R.H, Li, Y.N, Shi, T.H. | | Deposit date: | 2023-05-02 | | Release date: | 2024-07-10 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Overall structure of the LAT1-4F2hc bound with tryptophan
To Be Published
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8SLV
 | | Structure of a salivary alpha-glucosidase from the mosquito vector Aedes aegypti. | | Descriptor: | 1,3-PROPANDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Gittis, A.G, Williams, A.E, Garboczi, D, Calvo, E. | | Deposit date: | 2023-04-24 | | Release date: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Structural and functional comparisons of salivary alpha-glucosidases from the mosquito vectors Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus.
Insect Biochem.Mol.Biol., 167, 2024
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8ORP
 | | Crystal structure of Drosophila melanogaster alpha-amylase in complex with the inhibitor acarbose | | Descriptor: | 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... | | Authors: | Aghajari, N, Haser, R. | | Deposit date: | 2023-04-16 | | Release date: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and Functional Characterization of Drosophila melanogaster alpha-Amylase.
Molecules, 28, 2023
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8OR6
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8SDB
 | | Crystal Structure of E.Coli Branching Enzyme in complex with malto-octose | | Descriptor: | 1,4-alpha-glucan branching enzyme GlgB, alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | Authors: | Bingham, C.R, Nayebi, H, Fawaz, R, Geiger, J.H. | | Deposit date: | 2023-04-06 | | Release date: | 2023-07-12 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Structure of Maltooctaose-Bound Escherichia coli Branching Enzyme Suggests a Mechanism for Donor Chain Specificity.
Molecules, 28, 2023
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8CQG
 | | Crystal Structure of a Chimeric Alpha-Amylase from Pseudoalteromonas Haloplanktis | | Descriptor: | 1,2-ETHANEDIOL, Alpha-amylase, CALCIUM ION, ... | | Authors: | Skagseth, S, Lund, B.A, Griese, J.J, van der Ent, F, Aqvist, J. | | Deposit date: | 2023-03-06 | | Release date: | 2023-06-21 | | Last modified: | 2023-07-12 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Computational design of the temperature optimum of an enzyme reaction.
Sci Adv, 9, 2023
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8CQF
 | | Crystal Structure of a Chimeric Alpha-Amylase from Pseudoalteromonas Haloplanktis Complexed with Rearranged Acarbose | | Descriptor: | 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-1,5-anhydro-D-glucitol, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | Authors: | Skagseth, S, Griese, J.J, Lund, B.A, van der Ent, F, Aqvist, J. | | Deposit date: | 2023-03-06 | | Release date: | 2023-06-21 | | Last modified: | 2023-07-12 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Computational design of the temperature optimum of an enzyme reaction.
Sci Adv, 9, 2023
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8IM8
 | | Crystal structure of Periplasmic alpha-amylase (MalS) from E.coli | | Descriptor: | CALCIUM ION, Periplasmic alpha-amylase | | Authors: | An, Y, Park, J.T, Park, K.H, Woo, E.J. | | Deposit date: | 2023-03-06 | | Release date: | 2023-05-24 | | Last modified: | 2023-06-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Distinctive Permutated Domain Structure of Periplasmic alpha-Amylase (MalS) from Glycoside Hydrolase Family 13 Subfamily 19.
Molecules, 28, 2023
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8IDS
 | | Crystal structure of Bacillus sp. AHU2216 GH13_31 Alpha-glucosidase E256Q/N258P in complex with maltotriose | | Descriptor: | Alpha-glucosidase, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Auiewiriyanukul, W, Saburi, W, Yu, J, Kato, K, Yao, M, Mori, H. | | Deposit date: | 2023-02-14 | | Release date: | 2023-05-03 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Alteration of Substrate Specificity and Transglucosylation Activity of GH13_31 alpha-Glucosidase from Bacillus sp. AHU2216 through Site-Directed Mutagenesis of Asn258 on beta → alpha Loop 5.
Molecules, 28, 2023
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8IDA
 | | Overall structure of the LAT1-4F2hc bound with tyrosine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, Large neutral amino acids transporter small subunit 1, ... | | Authors: | Yan, R.H, Li, Y.N, Shi, T.H. | | Deposit date: | 2023-02-12 | | Release date: | 2024-07-10 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Overall structure of the LAT1-4F2hc bound with tyrosine
To Be Published
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